Using High Resolution Function Imaging To Detect Melanoma and Dysplastic Nevi

NCT01118832 | Completed

• 3 other identifiers: J0868R01CA161265-02NA_00016040
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

A novel infrared imaging tool to aid in the clinical detection of atypical pigmented lesions and melanoma is developed. Goals include evaluation of the utility of high-resolution infrared scanning of cutaneous lesions in the diagnosis of pigmented lesions and the identification of high-risk lesions and melanomas.

Conditions

Melanoma

Keywords

Thermography

Outcome Measures

Primary Outcomes (1)

• Ability to Detect of the melanoma lesions

  Using activated cooling methods we are measuring skin surface temperature recovery of specific lesions and comparing them to biopsy results of the lesions in question.

  up to 2 years

Secondary Outcomes (1)

• Measurement of thermal signatures of benign cutaneous lesions

  up to 2 years

Eligibility Criteria

• Age: 10 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The subject population will be identified in the Department of Dermatology Pigmented Lesion Clinic at the Johns Hopkins Hospital Outpatient Center. Recruited patients will only comprise those requesting a cutaneous pigmented lesion removed or patients that are examined and found to have a pigmented lesion that is suspicious for malignancy at the time of their visit, and thus recommended to have a skin biopsy for diagnosis following the standard of care

You may qualify if:

• Patients seen in the high-risk pigmented lesion clinic, who posses a pigmented lesion with a clinical indication for biopsy

You may not qualify if:

• None

Sponsors & Collaborators

• Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: lead
• Johns Hopkins University: collaborator
• National Cancer Institute (NCI): collaborator

Study Sites (1)

Johns Hopkins Medicine

Baltimore, Maryland, 21287, United States

Location

Related Publications (2)

• C HERMAN, THREE-DIMENSIONAL THERMAL IMAGING FOR THE DETECTION OF SKIN LESIONS AND OTHER NATURAL AND ABNORMAL CONDITIONS - WO Patent WO/2012/009,359, 2012

  BACKGROUND

• Herman C. Emerging technologies for the detection of melanoma: achieving better outcomes. Clin Cosmet Investig Dermatol. 2012;5:195-212. doi: 10.2147/CCID.S27902. Epub 2012 Nov 12.

  PMID: 23204850 RESULT

Related Links

• Video article describing the melanoma scanner
• Review article discussing emerging technologies for the detection of melanoma
• Johns Hopkins News release about the infrared scanner for detection of skin cancer

MeSH Terms

Conditions

Melanoma

Condition Hierarchy (Ancestors)

Neuroendocrine Tumors; Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Nerve Tissue; Nevi and Melanomas; Skin Neoplasms; Neoplasms by Site; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Cila Herman, Dr-Ing.

  Johns Hopkins University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 5, 2010
• First Posted: May 7, 2010
• Study Start: September 22, 2009
• Primary Completion: June 29, 2010
• Study Completion: February 20, 2012
• Last Updated: February 8, 2019

Record last verified: 2019-02

Locations

US (1)