Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

26.4%

156 terminated/withdrawn out of 590 trials

Success Rate

67.2%

-19.3% vs industry average

Late-Stage Pipeline

1%

6 trials in Phase 3/4

Results Transparency

72%

229 of 320 completed trials have results

Key Signals

68 recruiting229 with results122 terminated34 withdrawn

Enrollment Performance

Analytics

Phase 2
234(44.1%)
Phase 1
175(33.0%)
N/A
92(17.3%)
Early Phase 1
24(4.5%)
Phase 3
6(1.1%)
531Total
Phase 2(234)
Phase 1(175)
N/A(92)
Early Phase 1(24)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (590)

Showing 20 of 590 trials
NCT07512154Not ApplicableRecruiting

Precision Radiotherapy Enabled by Molecular MRI

Role: lead

NCT06205836Phase 2Recruiting

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

Role: lead

NCT03610711Phase 1Active Not Recruiting

REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer

Role: lead

NCT07281768Phase 2Not Yet Recruiting

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

Role: lead

NCT07430202Phase 1Not Yet Recruiting

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

Role: lead

NCT06941857Phase 2Recruiting

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

Role: lead

NCT07424222Phase 1Not Yet Recruiting

Ruxolitinib for Immune Effector Cell Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (RISE)

Role: lead

NCT07375992Not ApplicableNot Yet Recruiting

Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)

Role: lead

NCT03521830Phase 2Recruiting

Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

Role: lead

NCT06895564Not ApplicableRecruiting

Proton SBRT for Spinal Metastasis

Role: lead

NCT05014776Phase 2Completed

Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer

Role: lead

NCT07550517Phase 2Not Yet Recruiting

PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT

Role: lead

NCT03961971Phase 1Active Not Recruiting

Trial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM

Role: lead

NCT07209189Phase 2Recruiting

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Role: lead

NCT06796543Not ApplicableRecruiting

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

Role: lead

NCT05917301Not ApplicableRecruiting

Pre-operative Hypofractionated Proton Therapy

Role: lead

NCT06610682Early Phase 1Recruiting

A Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-altered Glioma

Role: lead

NCT07360119Not ApplicableNot Yet Recruiting

Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors

Role: lead

NCT06122480Not ApplicableTerminated

Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma

Role: lead

NCT04713046Phase 1Active Not Recruiting

Safety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers

Role: lead