Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

26.3%

157 terminated/withdrawn out of 597 trials

Success Rate

67.2%

-19.4% vs industry average

Late-Stage Pipeline

1%

6 trials in Phase 3/4

Results Transparency

74%

236 of 321 completed trials have results

Key Signals

69 recruiting236 with results123 terminated34 withdrawn

Enrollment Performance

Analytics

Phase 2
238(44.3%)
Phase 1
175(32.6%)
N/A
93(17.3%)
Early Phase 1
25(4.7%)
Phase 3
6(1.1%)
537Total
Phase 2(238)
Phase 1(175)
N/A(93)
Early Phase 1(25)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (597)

Showing 20 of 597 trials
NCT07852975Not ApplicableNot Yet Recruiting

GLAD-KE GLioma Biomarker and Safety Assessment During Dietary Ketone Elevation Subtitle: A Surgical Biomarker Discovery Study of Ketogenic Therapy in Recurrent Glioma

Role: lead

NCT05081193Phase 2Active Not Recruiting

Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer

Role: lead

NCT07140315Phase 1Recruiting

DK222 Study at Hopkins

Role: lead

NCT06398457Early Phase 1Recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Role: lead

NCT03573648Phase 2Active Not Recruiting

Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer

Role: lead

NCT07836101Phase 2Not Yet Recruiting

Study of Sarilumab With Immune Checkpoint Inhibitor Rechallenge in Patients With Clinically Significant Immune Related Adverse Events

Role: lead

NCT07734870Phase 2Recruiting

Tirzepatide for Treatment of CCCA

Role: collaborator

NCT06610682Early Phase 1Recruiting

A Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-altered Glioma

Role: lead

NCT05977907Phase 2Active Not Recruiting

Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).

Role: lead

NCT07550517Phase 2Recruiting

PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT

Role: lead

NCT05141513Phase 1Active Not Recruiting

Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

Role: lead

NCT03377517Not ApplicableTerminated

Radiosurgical Hypophysectomy for Bone Metasteses Pain

Role: lead

NCT04995198Recruiting

PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness

Role: collaborator

NCT02259621Phase 2Active Not Recruiting

Neoadjuvant Nivolumab, or Nivolumab in Combination With Ipilimumab, in Resectable NSCLC

Role: lead

NCT03875287Phase 1Active Not Recruiting

Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors

Role: lead

NCT07360119Not ApplicableRecruiting

Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors

Role: lead

NCT05386719Not ApplicableRecruiting

Cardiometabolic Screening Program

Role: lead

NCT06245889Phase 2Recruiting

PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC

Role: lead

NCT06138067Not ApplicableRecruiting

Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients

Role: lead

NCT04209686Phase 2Completed

Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma

Role: lead