NCT01110122

Brief Summary

Rationale: During exercise protein breakdown in muscles is larger than protein synthesis. This negative muscle protein balance leads to increased muscle damage and thereby to a reduced muscle tissue recovery. To achieve a positive muscle protein balance and reduce muscle damage, many athletes use proteins. In professional soccer players, considerable stress is placed on the musculoskeletal system. Recovery time is often too short for these players to restore homeostasis, which results in catabolic processes. This increases playing errors and will lead to lapses in concentration. Therefore, it is of great importance for a professional soccer team to be in optimal condition and a fast recovery after exercise is desirable to accomplish maximum performance. Supplementation with whey proteins is thought to support this. Objective: To assess whether post-exercise supplementation with whey protein will lead to a better muscle recovery than supplementation with carbohydrates in Dutch soccer players between the age of 15 and 18 years old. Study design: A double blind randomised controlled cross-over trial. Study population: Healthy soccer players of the A and B selection of AJAX between the age of 15 and 18 years old. Intervention: Supplement, containing either whey proteins or an isocaloric carbohydrate placebo. Each supplement will be administered for 2 weeks separated by a 7 day washout period. Treatment order will be randomly assigned. Main study parameters: The main study parameter will be the Yo-Yo intermittent recovery test level 2 score and the vertical jump test. The scores will evaluate the soccer players' ability to repeatedly perform intense exercise and his potential to recover from this exercise.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2010

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2010

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

April 22, 2010

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 26, 2010

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2010

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2010

Completed
Last Updated

April 26, 2010

Status Verified

March 1, 2010

Enrollment Period

3 months

First QC Date

April 22, 2010

Last Update Submit

April 22, 2010

Conditions

Keywords

Muscle recoveryIntermittent exerciseWhey proteinSoccer

Outcome Measures

Primary Outcomes (1)

  • Muscle recovery

    Recovery will be measured with the test scores on the Yo-Yo Intermittent Recovery Test level 2 and the Countermovement Jumping Test.

    2 weeks

Interventions

Whey proteinDIETARY_SUPPLEMENT

20g, oral, dissolved in yoghurt-drink, after every training and match for 2 weeks

Eligibility Criteria

Age15 Years - 19 Years
Sexmale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • performing soccer \>1 year
  • part of A \& B selection of AJAX

You may not qualify if:

  • presence of lactose intolerance
  • presence of illness
  • presence of injury

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ajax

Amsterdam, Netherlands

RECRUITING

MeSH Terms

Interventions

Whey Proteins

Intervention Hierarchy (Ancestors)

Milk ProteinsAnimal Proteins, DietaryDietary ProteinsProteinsAmino Acids, Peptides, and ProteinsWheyMilkDairy ProductsFoodDiet, Food, and NutritionPhysiological PhenomenaFood and Beverages

Study Officials

  • Ingeborg A Brouwer, PhD

    VU University of Amsterdam

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ingeborg A Brouwer, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 22, 2010

First Posted

April 26, 2010

Study Start

March 1, 2010

Primary Completion

June 1, 2010

Study Completion

July 1, 2010

Last Updated

April 26, 2010

Record last verified: 2010-03

Locations