Effects of a Dietary Supplement Containing L-Arabinose and Trivalent Patented Food-source of Chromium on Blood Glucose and Insulin

NCT01107431 | Completed

• 1 other identifier: Pharmachem 40-47
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

This study was designed to examine changes in capillary blood glucose and venous insulin levels after a 70 gram oral sucrose challenge with and without simultaneous consumption of a dietary supplement containing L-Arabinose and a patented version of chromium (LA-Cr).

Conditions

Pre-diabetes

Keywords

glucose; insulin; L-arabinose; Chromium

Outcome Measures

Primary Outcomes (1)

• Fasting Blood Glucose

  Finger-stick glucose measurements taken every 15 or 30 minutes after taking a 70 gram sucrose challenge with and without the dietary supplement

  Every 15 to 30 minutes

Secondary Outcomes (1)

• Fasting Blood Insulin Levels

  Every 30 minutes

Study Arms (2)

Sucrose with Dietary Supplement

ACTIVE COMPARATOR

Repeated measures on subjects taking 70 grams of sucrose along with taking a dietary supplement containing L-Arabinose and Chromium

Dietary Supplement: L-Arabinose and Chromium

Sucrose without Dietary Supplement

ACTIVE COMPARATOR

Consumed 70 grams of sucrose without simultaneously taking the dietary supplement

Dietary Supplement: Sucrose without dietary Supplement

Interventions

L-Arabinose and Chromium DIETARY_SUPPLEMENT

Consumed 70 grams of sucrose simultaneously taking a dietary supplement

Also known as: 70 grams of cane sugar along with supplement

Sucrose with Dietary Supplement

Sucrose without dietary Supplement DIETARY_SUPPLEMENT

Repeated measures on subjects taking 70 grams of sucrose along with taking a dietary supplement containing L-Arabinose and Chromium

Also known as: 70 grams of cane sugar with supplement

Sucrose without Dietary Supplement

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• All study subjects were required to contact their family physician to ensure they had no medical conditions that would preclude their participation.

You may not qualify if:

• Diabetics, and
• Those not approved by their physicians.

Sponsors & Collaborators

• Integrative Health Technologies, Inc.: lead

Study Sites (1)

Integrative Health Technologies

San Antonio, Texas, 78209, United States

Location

Related Publications (1)

• Kaats GR, Keith SC, Keith PL, Leckie RB, Perricone NV, Preuss HG. A combination of l-arabinose and chromium lowers circulating glucose and insulin levels after an acute oral sucrose challenge. Nutr J. 2011 May 6;10:42. doi: 10.1186/1475-2891-10-42.

  PMID: 21548959 DERIVED

MeSH Terms

Conditions

Glucose Intolerance; Insulin Resistance

Interventions

Arabinose; Chromium; Sucrose; Dietary Supplements

Condition Hierarchy (Ancestors)

Hyperglycemia; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Hyperinsulinism

Intervention Hierarchy (Ancestors)

Pentoses; Monosaccharides; Sugars; Carbohydrates; Metals, Heavy; Elements; Inorganic Chemicals; Transition Elements; Metals; Disaccharides; Oligosaccharides; Polysaccharides; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Gilbert R Kaats, PhD

  Integrative Health Technologies

  PRINCIPAL INVESTIGATOR

• Harry G Preuss, MD

  Georgetown University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: NETWORK

Study Record Dates

• First Submitted: April 19, 2010
• First Posted: April 21, 2010
• Study Start: December 1, 2008
• Primary Completion: December 1, 2009
• Study Completion: December 1, 2009
• Last Updated: May 13, 2011

Record last verified: 2011-05

Locations

US (1)