ADHD - Voice Analysis, Vocal Acoustic Biomarkers in Attention Deficit Hyperactivity Disorder

NCT01104623 | Unknown DMC

• 1 other identifier: AiF KF2247401-AK9-1
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to detect specific vocal acoustic patterns in the voice of attention deficit hyperactivity disorder (ADHD) patients.

Conditions

Attention-Deficit/Hyperactivity Disorder

Keywords

ADHD

Study Arms (2)

ADHD - Patients

Adults (18-50 years old). All eligible subjects will experience the voice recording procedure followed by the assessment of adult ADHD diagnostics. The diagnostic guidelines for ADHD in adulthood will be accomplished as outlined by expert consensus of the German Society for Psychiatry, Psychotherapy and Neurology, with a semi-structured clinical interview following the DSM-IV-TR criteria and the ADHD-Checklist (ADHD-CL) for DSM-IV (Hesslinger et al., 2002) to assess the severity of ADHD-Symptoms. Childhood ADHD symptoms will be rated retrospectively amongst others by using the short version (WURS-k) of the Wender Utah Rating Scale (Ward et al., 1993), German version (Retz-Junginger et al., 2002). To strengthen the validity of the ADHD diagnosis the reported symptoms were corroborated by second party reports.

Healthy Controls

Adults(18-50 years old). All eligible subjects will experience the voice recording procedure followed by the ADHD-Checklist (ADHD-CL) for DSM-IV (Hesslinger et al., 2002. To assess the severity of Non-ADHD, the absence of childhood ADHD symptoms will be rated retrospectively amongst others by using the short version (WURS-k) of the Wender Utah Rating Scale (Ward et al., 1993), German version (Retz-Junginger et al., 2002).

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

German speaking: Adults, age 18-50 years.

You may qualify if:

• Age 18-50.
• Written informed consent.
• Adult ADHD / Non-ADHD according to the fourth version of the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV)
• Normal vocal functioning, negative history for voice or laryngeal disorders.
• Currently euthyroid condition; in case of past history of thyroid disease and need for current pharmacological treatment, patient needs to be on stable medication for at least 4 weeks.

Sponsors & Collaborators

• Charite University, Berlin, Germany: lead
• MediTECH Electronic GmbH: collaborator
• AudioProfiling, Dr. Joerg Langner: collaborator

Study Sites (1)

Center for ADHD Research, Department of Psychiatry, Charite - University Medicine

Berlin, 14050, Germany

RECRUITING

Related Publications (2)

• Hamdan AL, Deeb R, Sibai A, Rameh C, Rifai H, Fayyad J. Vocal characteristics in children with attention deficit hyperactivity disorder. J Voice. 2009 Mar;23(2):190-4. doi: 10.1016/j.jvoice.2007.09.004. Epub 2007 Dec 21.

  PMID: 18082369 BACKGROUND

• Banse R, Scherer KR. Acoustic profiles in vocal emotion expression. J Pers Soc Psychol. 1996 Mar;70(3):614-36. doi: 10.1037//0022-3514.70.3.614.

  PMID: 8851745 BACKGROUND

Related Links

• ADHD - Voice Analysis

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Mental Disorders

Study Officials

• Michael Colla, PhD

  Center for ADHD Research, Department of Psychiatry, Charite - University Medicine Berlin

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: April 14, 2010
• First Posted: April 15, 2010
• Study Start: April 1, 2010
• Primary Completion: November 1, 2012
• Study Completion: December 1, 2012
• Last Updated: February 8, 2012

Record last verified: 2012-02

Locations

DE (1)