NCT01092169

Brief Summary

Sickle cell nephropathy is a known complication of sickle cell anemia (SCA) manifested by increase in glomerular filtration rate (glomerular hyperfiltration) and results in proteinuria and chronic renal failure. Our goal is to examine the prevalence of proteinuria and microalbuminuria as an early predictive factor of glomerular injury, among young people who suffer from SCA as well as those who suffer from combined sickle cell/beta-thalassemia.

Trial Health

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 23, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 24, 2010

Completed
Last Updated

March 24, 2010

Status Verified

March 1, 2010

First QC Date

March 23, 2010

Last Update Submit

March 23, 2010

Conditions

Study Arms (1)

Sickle cell beta

Other: No intervention

Interventions

Sickle cell beta

Eligibility Criteria

AgeUp to 25 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Young people suffering from SCA as well as those who suffer from combined sickle cell/beta-thalassemia, between 0-25 years old.

You may qualify if:

  • Patients diagnosed with sickle cell anemia
  • Patients diagnosed with combined sickle cell anemia/beta-thalassemia

You may not qualify if:

  • Diabetes mellitus
  • Hypertension
  • Reduced renal mass (single kidney)
  • Overweight
  • History of UTIs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Anemia, Sickle Cellbeta-Thalassemia

Condition Hierarchy (Ancestors)

Anemia, Hemolytic, CongenitalAnemia, HemolyticAnemiaHematologic DiseasesHemic and Lymphatic DiseasesHemoglobinopathiesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesThalassemia

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

March 23, 2010

First Posted

March 24, 2010

Last Updated

March 24, 2010

Record last verified: 2010-03