Sickle Cell Anemia
142
9
14
96
Key Insights
Highlights
Success Rate
86% trial completion
Published Results
29 trials with published results (20%)
Research Maturity
96 completed trials (68% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 62/100
10.6%
15 terminated out of 142 trials
86.5%
-0.0% vs benchmark
13%
19 trials in Phase 3/4
30%
29 of 96 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 96 completed trials
Clinical Trials (142)
Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Alendronate for Osteonecrosis in Adults With Sickle Cell Disease
A Long-term Follow-up Study in Participants Who Received CTX001
Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease
Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia
Blood Sampling for Research Related to Sickle Cell Disease
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Pociredir
The Montreal Cognitive Assessment.Test in Adults With Sickle Cell Disease
Serial Assessment of Fertility Experiences
Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease
Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia
Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype
The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell Hemoglobin C Disease (SC)
Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)
Stroke Prevention in Young Adults With Sickle Cell Anemia
Awake Prone Positioning for Severe Acute Chest Syndrome
Sickle Cell Disease (SCD) Bone Pain Study
SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia