FS
The Effect of Meal Viscosity on Postprandial Metabolic, Gut Hormone and Satiety Responses to Low and High Glycemic Index Preload Meals in Overweight Pre- and Post-menopausal Women.
Sponsor study identifier
interventional
22
1 country
1
Study Start
August 1, 2008
Actual (reported)Primary Completion
December 1, 2018
Actual (reported)Study Completion
December 19, 2018
Actual (reported)In this research study, investigators are interested in how certain dietary fibers in the diet affect certain hormones released from your intestine after eating and how these influence your appetite. The study hypothesis is that certain fibers will slow digestion and absorption of nutrients thereby optimizing fullness,reducing food intake and limiting insulin response in pre- and post-menopausal women.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 19, 2018
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 1, 2008
Actual (reported)January 13, 2010
Actual (reported)January 15, 2010
Actual (reported)December 1, 2018
Actual (reported)December 19, 2018
Actual (reported)To investigate the effects of viscous polysaccharide fibers on postprandial satiety.
Effect of Different Treatments on Cholecystokinin (CCK) Concentration
0, 20, 40, 60, 90, 120, 150, 180, 210, 240 minutes
To investigate the effects of viscous polysaccharide fibers on postprandial meal-associated metabolic response patterns.
Plasma glucose, insulin, and triglyceride concentrations measured by Randox Clinical analyzer
0, 20, 40, 60, 90, 120, 150, 180, 210, 240 minutes
To characterize the subjective and behavioral satiety responses to study-specific preload meals varying in viscous fiber content as well as determine the relationship of these satiety responses to the preload-associated physiological responses.
0, 20, 40, 60, 90, 120, 150, 180, 210, 240 minutes
No fiber control meal
80:20 ratio of viscous polysaccharide fiber to insoluble non-viscous producing fiber
20:80 ratio of viscous polysaccharide fiber source to insoluble non-viscous producing fiber
The High GI low fiber meal consists of 0 grams fiber with total kcal of 573 with 63% energy from carbohydrates, 24% energy from fat and 13% energy from protein. Test meal consists of breakfast meals containing muffins and yogurt beverage/shake.
Test meal consists of 12 grams of fiber (9 grams soluble and 3 grams insoluble). The ratio is 80:20 ratio of viscous polysaccharide fiber source (psyllium husk) to insoluble non-viscous producing fiber source (cellulose). Total kcal provided as 560 kcal with 63% energy from carbohydrates, 24% energy from fat and 13% energy from protein. Test meal consists of breakfast meals containing muffins and yogurt beverage/shake.
Clinical Nutrition Research Center
Chicago, Illinois, 60616, United States
Almiron-Roig E, Chen Y, Drewnowski A. Liquid calories and the failure of satiety: how good is the evidence? Obes Rev. 2003 Nov;4(4):201-12. doi: 10.1046/j.1467-789x.2003.00112.x.
Anderson GH, Moore SE. Dietary proteins in the regulation of food intake and body weight in humans. J Nutr. 2004 Apr;134(4):974S-9S. doi: 10.1093/jn/134.4.974S.
Burton-Freeman B. Sex and cognitive dietary restraint influence cholecystokinin release and satiety in response to preloads varying in fatty acid composition and content. J Nutr. 2005 Jun;135(6):1407-14. doi: 10.1093/jn/135.6.1407.
Britt Burton-Freeman, MS, PhD
Illinois Institute of Technology
22 participants (actual enrollment reported by the registry).
First Submitted
January 13, 2010
First Posted
January 15, 2010
Study Start
August 1, 2008
Actual (reported)Guided Imagery Training for Shooting Accuracy and Mental Skills in Adolescent Football Players
Test meal consists of 11 grams of fiber (3 grams soluble and 8 grams insoluble). The ratio is 20:80 of viscous polysaccharide fiber source (psyllium husk) to insoluble non-viscous producing fiber source (cellulose). Total kcal provided as 560 kcal with 63% energy from carbohydrates, 24% energy from fat and 13% energy from protein. Test meal consists of breakfast meals containing muffins and yogurt beverage/shake.
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Schneeman BO, Burton-Freeman B, Davis P. Incorporating dairy foods into low and high fat diets increases the postprandial cholecystokinin response in men and women. J Nutr. 2003 Dec;133(12):4124-8. doi: 10.1093/jn/133.12.4124.
Burton-Freeman B, Davis PA, Schneeman BO. Plasma cholecystokinin is associated with subjective measures of satiety in women. Am J Clin Nutr. 2002 Sep;76(3):659-67. doi: 10.1093/ajcn/76.3.659.
Burton-Freeman B, Davis PA, Schneeman BO. Interaction of fat availability and sex on postprandial satiety and cholecystokinin after mixed-food meals. Am J Clin Nutr. 2004 Nov;80(5):1207-14. doi: 10.1093/ajcn/80.5.1207.
Primary Completion
December 1, 2018
Actual (reported)Study Completion
December 19, 2018
Actual (reported)Last Updated
January 27, 2021
Record last verified: 2021-01
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Source: ClinicalTrials.gov.
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