Observational Study to Evaluate Bipolar Disorder Symptoms in Patients Presented With Schizophrenia or Depression

NCT01028196 | Completed

• 1 other identifier: NIS-NRU-DUM-2009/1
• Study Type: observational
• Target: 750
• Locations: 1 country
• Sites: 3

Brief Summary

This study is aimed to evaluate the bipolar disorder symptoms in patients presented with schizophrenia, schizoaffective disorder or recurrent depression. Bipolar disorder is a group of mood disorders characterised by elevated or irritable mood episodes in patient's lifetime history accompanied by some additional symptoms. In this study modern bipolar disorders screening/assessment instruments will be used to explore the prevalence of bipolarity symptoms in patients who never been diagnosed with bipolar disorders. The results of this study could be useful for more accurate assessment of bipolar disorders prevalence in psychiatric patient population, could help to improve the diagnostics of bipolar disorders and management of bipolar patients.

Conditions

Schizophrenia; Schizoaffective Disorder; Recurrent Depression

Keywords

schizophrenia; schizoaffective disorder; recurrent depression; Bipolar disorders

Study Arms (2)

1 - schizophrenia

Psychiatrists will enrol patients meeting inclusion/exclusion criteria with schizophrenia as they routinely attend the clinic or are examined in hospital in a consecutively manner.

2 - recurrent depression

Psychiatrists will enrol patients meeting inclusion/exclusion criteria with recurrent depression as they routinely attend the clinic or are examined in hospital in a consecutively manner.

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients having current diagnosis of schizophrenia/ schizoaffective disorder (in-patients) and patients having current diagnosis of recurrent depression (both in-patients and out-patients) will be included into this study.

You may qualify if:

• signed patient informed consent
• In-patients with the diagnosis of schizophrenia with episodic course or schizoaffective disorder, OR in-patients and out-patients with the diagnosis of recurrent depression.
• The duration of the disease is 3 years and longer and two or more episodes of the disease in the patients history.

You may not qualify if:

• Current diagnosis of Bipolar Disorder
• Severe and unspecified forms of schizophrenia (schizophrenia with continuous course, hebephrenic schizophrenia, catatonic schizophrenia, undifferentiated schizophrenia, unspecified schizophrenia) and organic affective disorder or intoxication induced affective disorder.
• Any other concomitant conditions which, in the judgment of investigator, will not allow the patient to complete the study procedures

Sponsors & Collaborators

• AstraZeneca: lead

Study Sites (3)

Research Site

Chita, Russia

Location

Research Site

Moscow, Russia

Location

Research Site

Novosibirsk, Russia

Location

MeSH Terms

Conditions

Schizophrenia; Psychotic Disorders; Depression; Bipolar Disorder

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders; Behavioral Symptoms; Behavior; Bipolar and Related Disorders; Mood Disorders

Study Officials

• Sergey N. Mosolov, Prof.

  Mental Disorders Moscow Research Institute of Psychiatry

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 7, 2009
• First Posted: December 9, 2009
• Study Start: November 1, 2009
• Primary Completion: November 1, 2010
• Study Completion: November 1, 2010
• Last Updated: November 1, 2011

Record last verified: 2011-10

Locations

RU (3)