Assessing the Effectiveness of Acceptance and Commitment Therapy for Distress Following Psychosis

NCT01003132 | Completed DMC

• 2 other identifiers: PN09CP213Ethics Ref:09/S0701/74
• Study Type: interventional
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

This research investigates a new talking therapy aimed at helping people to come to terms with the experience of psychosis. The new therapy is called Acceptance and Commitment Therapy for psychosis (PACT). PACT aims to help people:

1. 1.Develop a sense of "mindfulness." Mindfulness allows you to be fully aware of your here-and-now experience, with an attitude of openness and curiosity. It is hoped that this will help reduce the impact of painful thoughts and feelings.
2. 2.Take effective action that is conscious and deliberate, rather than impulsive. It is hoped that this will allow people to be motivated, guided, and inspired by the things that they value in life.

Conditions

Psychosis; Schizophrenia; Bipolar Disorder; Schizo-affective Disorder

Keywords

Psychosis; Distress; Mindfulness; Acceptance; Values

Outcome Measures

Primary Outcomes (2)

• Measuring change in depression and anxiety

  The Hospital Anxiety and Depression Scale

  Baseline and 3 month follow-up

• Changes in believability, distress and frequency of positive symptoms

  Baseline and up to 9 months follow-up

Secondary Outcomes (1)

• Measuring change in mindfulness skills and psychological flexibility

  Baseline and up to 9 month follow-up

Study Arms (2)

Treatment As Usual

NO INTERVENTION

Treatment as usual as determined by the clinical team responsible for the individual's care

Acceptance and Commitment Therapy

ACTIVE COMPARATOR

Up to 10 sessions of Acceptance and Commitment Therapy plus treatment as usual

Other: Acceptance and Commitment Therapy

Interventions

Acceptance and Commitment Therapy OTHER

Up to 10 sessions of a psychological therapy called Acceptance and Commitment Therapy

Also known as: ACT

Acceptance and Commitment Therapy

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Participants will meet DSM-IV-TR (APA, 2000) criteria for a psychotic disorder determined by a diagnosis of a psychotic disorder (i.e., Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Delusional Disorder, Brief Psychotic Disorder, Psychotic Disorder NOS) or Bipolar Disorder (with psychotic features).
• Participants will also be aged 18-65

You may not qualify if:

• Participants will be excluded if there is a
• diagnosis of learning disability
• inability to participate in psychotherapy/research due to acute medical condition or florid psychosis (as defined by a score of 5 or over on the Positive Syndrome scale of the PANSS)
• psychotic symptoms due to a general medical condition
• they are receiving a systematic psychological therapy at the point of recruitment/randomization.

Sponsors & Collaborators

• University of Glasgow: lead
• NHS Greater Glasgow and Clyde: collaborator

Study Sites (1)

Greater Glasgow and Clyde NHS

Glasgow, Scotland, G3 8YZ, United Kingdom

Location

Related Publications (3)

• Bach P, Hayes SC. The use of acceptance and commitment therapy to prevent the rehospitalization of psychotic patients: a randomized controlled trial. J Consult Clin Psychol. 2002 Oct;70(5):1129-39. doi: 10.1037//0022-006x.70.5.1129.

  PMID: 12362963 BACKGROUND

• Gaudiano BA, Herbert JD. Acute treatment of inpatients with psychotic symptoms using Acceptance and Commitment Therapy: pilot results. Behav Res Ther. 2006 Mar;44(3):415-37. doi: 10.1016/j.brat.2005.02.007.

  PMID: 15893293 BACKGROUND

• Hayes, S.C., Strosahl, K. and Wilson, K.G. (1999). Acceptance and Commitment Therapy: An experiential approach to behavior change, The Guilford Press, New York

  BACKGROUND

MeSH Terms

Conditions

Psychotic Disorders; Schizophrenia; Bipolar Disorder

Interventions

Acceptance and Commitment Therapy

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders; Bipolar and Related Disorders; Mood Disorders

Intervention Hierarchy (Ancestors)

Cognitive Behavioral Therapy; Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Ross G White, BSc, PhD, DClinPsy

  University of Glasgow

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: October 27, 2009
• First Posted: October 28, 2009
• Study Start: October 1, 2009
• Primary Completion: October 1, 2010
• Study Completion: October 1, 2010
• Last Updated: November 9, 2010

Record last verified: 2010-11

Locations

GB (1)