Biomarker in Lung Diseases
Feasibility Study on Establishing Biomarkers in Lung Diseases
1 other identifier
observational
120
1 country
1
Brief Summary
Disease related biomarkers have been established decades ago, e.g. blood glucose for diabetes diagnosis and management. Their discovery has grown dramatically during the past decade and they have the potential to lead the physician in diagnosis -especially differential diagnosis - and therapy. However, a specific serum-biomarker in lung diseases has not been established. Aim of the current study is to to measure lung specific proteins in the serum in patients with various lung diseases and to correlate those with disease severity, lung function and other laboratory results
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Oct 2009
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2009
CompletedFirst Submitted
Initial submission to the registry
October 5, 2009
CompletedFirst Posted
Study publicly available on registry
October 6, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2010
CompletedOctober 14, 2009
October 1, 2009
5 months
October 5, 2009
October 13, 2009
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Serum biomarker expression
1 month
Study Arms (1)
lung disease
patients with various chronic or acute lung diseases
Interventions
Eligibility Criteria
Patients with acute or chronic lung diseases
You may qualify if:
- age \>= 18
- acute or chronic lung disease
You may not qualify if:
- HIV
- lactation or gestation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Thoraxklinik Heidelberg, Dept. of Pneumology and Respiratory Critical care
Heidelberg, 69126, Germany
Related Publications (2)
Tzouvelekis A, Pneumatikos I, Bouros D. Serum biomarkers in acute respiratory distress syndrome an ailing prognosticator. Respir Res. 2005 Jun 22;6(1):62. doi: 10.1186/1465-9921-6-62.
PMID: 15972108BACKGROUNDTzouvelekis A, Kouliatsis G, Anevlavis S, Bouros D. Serum biomarkers in interstitial lung diseases. Respir Res. 2005 Jul 21;6(1):78. doi: 10.1186/1465-9921-6-78.
PMID: 16042760BACKGROUND
Biospecimen
Serum (blood)
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Michael Kreuter, MD
Thoraxklinik Heidelberg, Germany
- STUDY DIRECTOR
Felix JF Herth, MD
Thoraxklinik Heidelberg Germany
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
October 5, 2009
First Posted
October 6, 2009
Study Start
October 1, 2009
Primary Completion
March 1, 2010
Study Completion
June 1, 2010
Last Updated
October 14, 2009
Record last verified: 2009-10