Trials Sponsors Conditions Drugs Pricing

Conditions

Obesity

Keywords

Antibiotic ConcentrationTissueObesityCesarean

Outcome Measures

Primary Outcomes (1)

To assess the effects of maternal obesity on the concentrations and adequacy of antimicrobial activity of prophylactically administered antibiotics within tissues (subcutaneous adipose and myometrial) at the time of cesarean delivery.
6 weeks

Secondary Outcomes (1)

To assess the concentrations and adequacy of antimicrobial activity of prophylactically administered antibiotics within tissues (subcutaneous adipose and myometrial) at the time of cesarean delivery.
6 weeks

Study Arms (3)

BMI <30

BMI \<30

BMI 30-39

BMI >40

BMI \>40

Eligibility Criteria

Age18 Years+

Sexfemale

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

All patients requiring cesarean delivery under non-emergent circumstances

You may qualify if:

Patients at term (\> 37 weeks) undergoing a cesarean delivery.

You may not qualify if:

Sponsors & Collaborators

MemorialCare
Otherlead
University of California, Irvine
Othercollaborator

Study Sites (2)

Women's Pavilion at Miller Children's Hospital

Long Beach, California, 90806, United States

University of California Irvine Medical Center

Orange, California, 92868, United States

Related Publications (1)

Pevzner L, Swank M, Krepel C, Wing DA, Chan K, Edmiston CE Jr. Effects of maternal obesity on tissue concentrations of prophylactic cefazolin during cesarean delivery. Obstet Gynecol. 2011 Apr;117(4):877-882. doi: 10.1097/AOG.0b013e31820b95e4.
PMID: 21422859DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

Adipose, myometrial and blood serum samples

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

Kenneth Chan, MD
Long Beach Memorial Medical Center
PRINCIPAL INVESTIGATOR

Enrollment

31 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER

Study Record Dates

First Submitted

September 18, 2009

First Posted

September 21, 2009

Study Start

June 2009

Date type not reported

This date has not been verified as actual or estimated.

Obesity and Antibiotic Tissue Concentration

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (3)

BMI <30

BMI 30-39

BMI >40

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (2)

Related Publications (1)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (3)

BMI <30

BMI 30-39

BMI >40

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (2)

Related Publications (1)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations