NCT00976235

Brief Summary

This is a 5-year study of patients implanted with the Implantable Miniature Telescope (IMT by Dr. Isaac Lipshitz) under Protocol IMT-002. All patients implanted with the telescope prosthesis who enrolled in the IMT-002 trial were asked to participate in this study to monitor long-term safety. Patients will undergo examinations at six-month intervals up to a total of 5 years following implantation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
129

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2006

Longer than P75 for not_applicable

Geographic Reach
1 country

28 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2006

Completed
3.3 years until next milestone

First Submitted

Initial submission to the registry

September 10, 2009

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 14, 2009

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2011

Completed
Last Updated

November 6, 2017

Status Verified

November 1, 2017

Enrollment Period

4.9 years

First QC Date

September 10, 2009

Last Update Submit

November 1, 2017

Conditions

Keywords

Macular DegenerationVisual ImpairmentQuality of LifeTelescope Prosthesis

Outcome Measures

Primary Outcomes (1)

  • Long term safety (Intraocular pressure, Slit lamp, Endothelial Cell Density, Visual Acuity, Complications, Adverse Events and Device Failures)

    5 years from implantation

Study Arms (1)

IMT

EXPERIMENTAL
Device: IMT - Implantable Miniature Telescope

Interventions

Implantation of the telescope prosthesis (performed under the initial study)

IMT

Eligibility Criteria

Age55 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients must have participated in the IMT-002 trial.
  • Patients must be able to understand and comply with the requirements of the clinical study, and be able to abide by the requirements and restrictions of the study.
  • Patients must be able to provide voluntary informed consent, and must sign and be given a copy of the written Informed Consent form.

You may not qualify if:

  • Patients who have not participated in the IMT-002 trial.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (28)

Retina Centers P.C.

Tucson, Arizona, 85704, United States

Location

University of California at Irvine

Irvine, California, 92697, United States

Location

Altos Eye Physician

Los Altos, California, 94024, United States

Location

Doheny Retina Institute - University of Southern California

Los Angeles, California, 90033, United States

Location

Sarasota Retinal Institute

Sarasota, Florida, 34239, United States

Location

Emory Eye Center

Atlanta, Georgia, 30322, United States

Location

Kraft Eye Institute

Chicago, Illinois, 60634, United States

Location

Paducah Retinal Center

Paducah, Kentucky, 42001, United States

Location

Wilmer Ophthalmological Institute

Baltimore, Maryland, 21287-9277, United States

Location

Retina Group of Washington

Chevy Chase, Maryland, 20815, United States

Location

Massachusetts Eye & Ear Infirmary

Boston, Massachusetts, 02114, United States

Location

Ophthalmic Consultants of Boston

Boston, Massachusetts, 02114, United States

Location

W.K. Kellogg Eye Center

Ann Arbor, Michigan, 48105, United States

Location

Associated Retinal Consultants

Royal Oak, Michigan, 48073, United States

Location

Associated Eye Care

Stillwater, Minnesota, 55082, United States

Location

Discover Vision Centers

Independence, Missouri, 64055, United States

Location

Manhattan Eye & Ear

New York, New York, 10021, United States

Location

Southeast Clinical Research

Charlotte, North Carolina, 28210, United States

Location

Duke University Eye Center

Durham, North Carolina, 27710, United States

Location

Retina Associates of Cleveland

Beachwood, Ohio, 44122, United States

Location

Dean A. McGee Eye Institute

Oklahoma City, Oklahoma, 73104, United States

Location

Fine, Hoffman & Packer

Eugene, Oregon, 97401, United States

Location

Wills Eye Hospital

Philadelphia, Pennsylvania, 19107, United States

Location

Vitreoretinal Foundation

Memphis, Tennessee, 78240, United States

Location

Vanderbilt University

Nashville, Tennessee, 37232, United States

Location

Baylor College of Medicine

Houston, Texas, 77030, United States

Location

Medical Center Ophthalmology

San Antonio, Texas, 78240, United States

Location

Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States

Location

MeSH Terms

Conditions

Macular DegenerationVision Disorders

Condition Hierarchy (Ancestors)

Retinal DegenerationRetinal DiseasesEye DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 10, 2009

First Posted

September 14, 2009

Study Start

June 1, 2006

Primary Completion

May 1, 2011

Study Completion

May 1, 2011

Last Updated

November 6, 2017

Record last verified: 2017-11

Locations