NCT02555995

Brief Summary

Optical Coherence Tomography (OCT) is an established non-invasive medical imaging technique ophthalmologists use to diagnose and monitor retinal diseases such as age-related macular degeneration (AMD). This study assesses the scanning performance of a newly developed sparse OCT retina scanner that is smaller and more compact than most commercially available medical OCT systems. The prototype device was developed at Artorg Center Bern and Berner Fachhochschule Biel. In this study the device is first tested on human eyes. The scanning performance is compared to a reference device. Additionally patient feedback during the examination is acquired. The findings of this study are used to improve the software and the ergonomics of the investigational device.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 17, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 22, 2015

Completed
1 month until next milestone

Study Start

First participant enrolled

November 1, 2015

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2016

Completed
Last Updated

February 24, 2016

Status Verified

February 1, 2016

Enrollment Period

2 months

First QC Date

September 17, 2015

Last Update Submit

February 23, 2016

Conditions

Keywords

AMDOCT

Outcome Measures

Primary Outcomes (1)

  • Distance between ILM and RPE (IPD) measurement successful or not. Successful is defined as a) measurement performed/failed, and if performed, b) value obtained within ±10% of value of reference OCT device.

    During diagnostic intervention, expected to be ca. 30 minutes on average

Secondary Outcomes (2)

  • Patient comfort during examination

    Directly after diagnostic intervention, expected to be ca. 35 minutes on average

  • Duration of OCT examination with investigational device

    Directly after diagnostic intervention, expected to be ca. 35 minutes on average

Study Arms (1)

All study participants

EXPERIMENTAL

Patient's eyes are OCT-scanned with standard device and investigational device.

Device: OCT scan (as yet unnamed)

Interventions

OCT scan (as yet unnamed) of the eye with investigational device; newly developed sparse OCT retina scanner by Artorg Center Bern and Berner Fachhochschule Biel

All study participants

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older
  • German speaking
  • Suffering from age-related macular degeneration
  • Written informed consent

You may not qualify if:

  • Epilepsy
  • Parkinsonian syndrome
  • Dementia
  • Pregnant women
  • Persons using electronic medical aids i.e. hearing aid, pacemaker..

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Augenklinik Univestitätspital Zürich

Zurich, Canton of Zurich, 8006, Switzerland

Location

MeSH Terms

Conditions

Macular Degeneration

Condition Hierarchy (Ancestors)

Retinal DegenerationRetinal DiseasesEye Diseases

Study Officials

  • Sandrine Zweifel, MD

    Augenklinik Universitätspital Zürich

    PRINCIPAL INVESTIGATOR
  • Raphael Sznitman

    ARTORG, University of Bern

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 17, 2015

First Posted

September 22, 2015

Study Start

November 1, 2015

Primary Completion

January 1, 2016

Study Completion

January 1, 2016

Last Updated

February 24, 2016

Record last verified: 2016-02

Locations