NCT00899119

Brief Summary

RATIONALE: Collecting and storing stem cells to study in the laboratory may help doctors learn more about collecting stem cells from patients who have undergone treatment for Waldenstrom's macroglobulinemia. PURPOSE: This laboratory study is collecting stem cells from patients with Waldenstrom's macroglobulinemia.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2005

Completed
3.5 years until next milestone

First Submitted

Initial submission to the registry

May 9, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 12, 2009

Completed
Last Updated

December 18, 2013

Status Verified

January 1, 2008

First QC Date

May 9, 2009

Last Update Submit

December 17, 2013

Conditions

Lymphoma

Keywords

Waldenström macroglobulinemia

Outcome Measures

Primary Outcomes (1)

  • Number of days to adequate stem cell harvest

Interventions

leukapheresisPROCEDURE

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
DISEASE CHARACTERISTICS: * Diagnosis of Waldenstrom's macroglobulinemia (WM) * Less than 30% lymphoplasmacytoid cells in bone marrow by histopathology * Received prior chemotherapy for WM PATIENT CHARACTERISTICS: * ECOG performance status 0-1 * WBC \> 2,000/mm³ * Platelet count \> 50,000/mm³ * LVEF ≥ 50% * No organ dysfunction that would preclude future transplantation PRIOR CONCURRENT THERAPY: * See Disease Characteristics

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center

New York, New York, 10032, United States

RECRUITING

MeSH Terms

Conditions

LymphomaWaldenstrom Macroglobulinemia

Interventions

Leukapheresis

Condition Hierarchy (Ancestors)

Neoplasms by Histologic TypeNeoplasmsLymphoproliferative DisordersLymphatic DiseasesHemic and Lymphatic DiseasesImmunoproliferative DisordersImmune System DiseasesNeoplasms, Plasma CellHemostatic DisordersVascular DiseasesCardiovascular DiseasesParaproteinemiasBlood Protein DisordersHematologic DiseasesHemorrhagic Disorders

Intervention Hierarchy (Ancestors)

CytapheresisBiological TherapyTherapeuticsBlood Component RemovalLeukocyte Reduction ProceduresCell SeparationCytological TechniquesClinical Laboratory TechniquesInvestigative Techniques

Study Officials

  • Gwen L. Nichols, MD

    Herbert Irving Comprehensive Cancer Center

    STUDY CHAIR

Study Design

Study Type
observational
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 9, 2009

First Posted

May 12, 2009

Study Start

November 1, 2005

Last Updated

December 18, 2013

Record last verified: 2008-01

Locations

US(1)