Success Metrics

Clinical Success Rate
68.4%

Based on 39 completed trials

Completion Rate
68%(39/57)
Active Trials
44(34%)
Results Posted
64%(25 trials)
Terminated
18(14%)

Phase Distribution

Ph not_applicable
11
9%
Ph phase_2
26
20%
Ph phase_3
5
4%
Ph early_phase_1
4
3%
Ph phase_1
74
57%
Ph phase_4
1
1%

Phase Distribution

78

Early Stage

26

Mid Stage

6

Late Stage

Phase Distribution121 total trials
Early Phase 1First-in-human
4(3.3%)
Phase 1Safety & dosage
74(61.2%)
Phase 2Efficacy & side effects
26(21.5%)
Phase 3Large-scale testing
5(4.1%)
Phase 4Post-market surveillance
1(0.8%)
N/ANon-phased studies
11(9.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

59.1%

39 of 66 finished

Non-Completion Rate

40.9%

27 ended early

Currently Active

44

trials recruiting

Total Trials

129

all time

Status Distribution
Active(52)
Completed(39)
Terminated(27)
Other(11)

Detailed Status

Completed39
Recruiting35
Terminated18
Withdrawn9
Active, not recruiting9
Not yet recruiting7

Development Timeline

Analytics

Development Status

Total Trials
129
Active
44
Success Rate
68.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (3.3%)
Phase 174 (61.2%)
Phase 226 (21.5%)
Phase 35 (4.1%)
Phase 41 (0.8%)
N/A11 (9.1%)

Trials by Status

terminated1814%
recruiting3527%
completed3930%
enrolling_by_invitation11%
unknown54%
not_yet_recruiting75%
withdrawn97%
active_not_recruiting97%
suspended65%

Recent Activity

Clinical Trials (129)

Showing 20 of 129 trialsScroll for more
NCT06236139Phase 1

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

Recruiting
NCT06469710

A Trial to Evaluate the Effect of Applying Leukapheresis to Enrich CTCs in mPCa Patients

Recruiting
NCT07758673Phase 1

Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma

Not Yet Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT01087294Phase 1

Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation

Completed
NCT06871410Phase 1

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
NCT05773040Phase 1

A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas

Recruiting
NCT03226704

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

Enrolling By Invitation
NCT07098364Phase 1

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Recruiting
NCT06724237Phase 3

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

Recruiting
NCT07711483Phase 2

GLORY: Glofit-GemOx With Liso-Cel For Lymphoma

Not Yet Recruiting
NCT02650986Phase 1

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

Active Not Recruiting
NCT06043713Phase 1

Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations

Recruiting
NCT06930352Phase 2

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

Not Yet Recruiting
NCT03710421Phase 1

CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory CS1 Positive Multiple Myeloma

Suspended
NCT07316010Phase 2

Phase 2 Trial of Lisocabtagene Maraleucel for Minimal Residual Disease in Patients With Large B-cell Lymphoma

Recruiting
NCT07676877Phase 1

Lymphodepletion With Low Dose Total Body Irradiation Before Standard of Care Tisagenlecleucel for the Treatment of Relapsed and Recurrent Large B-cell Lymphoma

Not Yet Recruiting
NCT06815029Phase 1

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Recruiting
NCT05672459Phase 1

A Safety And Efficacy Study Of HLA-G- Targeted CAR-T Cells IVS-3001 In Subjects With Previously Treated Advanced HLA-G-Positive Solid Tumors

Active Not Recruiting
NCT02782546Phase 2

Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation

Active Not Recruiting

Drug Details

Intervention Type
DEVICE
Total Trials
129