Studying Blood Samples in Women With Breast Cancer or a History of Breast Cancer

NCT00898703 | Completed

• 3 other identifiers: CDR0000597587P30CA023074UARIZ-HSCA01134
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

RATIONALE: Studying samples of blood in the laboratory from patients with current or previous cancer may help doctors learn more about biomarkers related to cancer. PURPOSE: This research study is looking at blood samples in women with breast cancer or a history of breast cancer.

Conditions

Breast Cancer

Keywords

breast cancer

Outcome Measures

Primary Outcomes (1)

• Comparison of levels of peripheral blood (PB) circulating endothelial cells (CEC) and plasma angiogenic factors between patients with active, measurable breast cancer vs prior history of breast cancer with no evidence of active disease

Secondary Outcomes (1)

• Correlation of CEC and plasma angiogenic factors with response to tumor to a chemotherapy regimen

Interventions

flow cytometry OTHER

immunoenzyme technique OTHER

laboratory biomarker analysis OTHER

Eligibility Criteria

• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

women with breast cancer or a history of breast cancer

DISEASE CHARACTERISTICS: * Meets 1 of the following criteria: * Receiving treatment for measurable breast cancer at the Arizona Cancer Center Clinic * Being followed for a prior history of breast cancer (with no evidence of active disease) at the Arizona Cancer Center * Hormone receptor status not specified PATIENT CHARACTERISTICS: * Menopausal status not specified * Not pregnant or nursing PRIOR CONCURRENT THERAPY: * See Disease Characteristics

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• University of Arizona: lead
• National Cancer Institute (NCI): collaborator

Study Sites (1)

Arizona Cancer Center at University of Arizona Health Sciences Center

Tucson, Arizona, 85724, United States

Location

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Flow Cytometry; Immunoenzyme Techniques

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Cell Separation; Cytological Techniques; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Cytophotometry; Fluorometry; Luminescent Measurements; Photometry; Chemistry Techniques, Analytical; Investigative Techniques; Immunoassay; Immunologic Techniques; Immunohistochemistry; Molecular Probe Techniques

Study Officials

• Alison T. Stopeck, MD

  University of Arizona

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: May 9, 2009
• First Posted: May 12, 2009
• Study Start: August 1, 2001
• Primary Completion: March 1, 2007
• Study Completion: March 1, 2007
• Last Updated: December 17, 2012

Record last verified: 2012-12

Locations

US (1)