NCT00887848

Brief Summary

The purpose of the study is to investigate the effectiveness of robotic-assisted locomotor therapy on improvements of functional gait parameters in ambulatory children with cerebral palsy.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2009

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 23, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 24, 2009

Completed
5 months until next milestone

Study Start

First participant enrolled

October 5, 2009

Completed
7.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 14, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 14, 2017

Completed
Last Updated

March 30, 2018

Status Verified

March 1, 2018

Enrollment Period

7.9 years

First QC Date

April 23, 2009

Last Update Submit

March 28, 2018

Conditions

Keywords

ChildRobotic-assisted treadmill trainingRehabilitation

Outcome Measures

Primary Outcomes (1)

  • GMFM-66, section E

    week 0, week 6, week 12

Secondary Outcomes (4)

  • GMFM-66, section D

    week 0, week 6, week 12

  • Gait speed

    week 0, week 6, week 12

  • 6-minute walk test

    week 0, week 6, week 12

  • 3D gait analysis

    week 0, week 6

Study Arms (2)

Lokomat training

EXPERIMENTAL

Lokomat training

Other: Lokomat training

Waiting list

OTHER

Lokomat training after waiting phase of 5 weeks

Other: Lokomat training

Interventions

15 sessions of Lokomat training within 5 weeks (3 trainings/week)

Lokomat trainingWaiting list

Eligibility Criteria

Age6 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Bilateral spastic cerebral palsy
  • Gross Motor Function Classification Scale (GMFCS) II-IV

You may not qualify if:

  • Prior orthopedic surgery on the lower extremity or the trunk (\<6 months)
  • Prior neurosurgical interventions (\<6 months)
  • Significant mental retardation
  • Severe contractures
  • Prior Lokomat training (\<6 months)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Paediatric Therapy Center Reha Rheinfelden

Rheinfelden, Canton of Aargau, CH-4310, Switzerland

Location

University Children's Hospital Zurich, Rehabilitation Centre Affoltern

Affoltern am Albis, CH-8910, Switzerland

Location

Related Publications (2)

  • Ammann-Reiffer C, Bastiaenen CHG, Meyer-Heim AD, van Hedel HJA. Lessons learned from conducting a pragmatic, randomized, crossover trial on robot-assisted gait training in children with cerebral palsy (PeLoGAIT). J Pediatr Rehabil Med. 2020;13(2):137-148. doi: 10.3233/PRM-190614.

  • Ammann-Reiffer C, Bastiaenen CH, Meyer-Heim AD, van Hedel HJ. Effectiveness of robot-assisted gait training in children with cerebral palsy: a bicenter, pragmatic, randomized, cross-over trial (PeLoGAIT). BMC Pediatr. 2017 Mar 2;17(1):64. doi: 10.1186/s12887-017-0815-y.

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Corinne Ammann-Reiffer, MPTSc

    University Children's Hospital Zurich, Rehabilitation Center Affoltern

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 23, 2009

First Posted

April 24, 2009

Study Start

October 5, 2009

Primary Completion

August 14, 2017

Study Completion

August 14, 2017

Last Updated

March 30, 2018

Record last verified: 2018-03

Locations