Effect of Red Raspberry Consumption on Fasting Oxidative Stress Biomarkers
Raspberries and Human Health: A Short-term Intervention Trial Investigating the Effect of Daily Red Raspberry Consumption on Fasting Oxidative Stress Biomarkers
1 other identifier
interventional
24
1 country
1
Brief Summary
The purpose of this study is determine whether daily consumption of frozen red raspberries can improve the antioxidant capacity of the blood and reduce the effects of oxidative stress, dose-dependently, in a healthy adult population.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_1
Started Mar 2009
Shorter than P25 for phase_1
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2009
CompletedFirst Submitted
Initial submission to the registry
April 3, 2009
CompletedFirst Posted
Study publicly available on registry
April 7, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2009
CompletedOctober 29, 2010
October 1, 2010
2 months
April 3, 2009
October 28, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
serum TBARS
an indicator of MDA levels, and therefore, lipid peroxidation
end of week 1, 3, 5 and 9
Secondary Outcomes (2)
serum antioxidant capacity (AOC)
end of week 1, 3, 5 and 9
serum thiols
end of week 1, 3, 5 and 9
Study Arms (3)
one-cup
EXPERIMENTALtwo-cups
EXPERIMENTALfour-cups
EXPERIMENTALInterventions
Consumption of one-cup frozen red raspberries daily for four weeks, followed by a four week period of non-treatment.
Eligibility Criteria
You may qualify if:
- healthy adults
You may not qualify if:
- obese (\>30kg/m2)
- high blood pressure (140/90mmHg)
- allergic to raspberries
- pregnant or lactating
- history of chronic disease
- currently taking medication
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Torontolead
- Unity Health Torontocollaborator
Study Sites (1)
Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital
Toronto, Ontario, M5C 2T2, Canada
Study Officials
- PRINCIPAL INVESTIGATOR
A V Rao, PhD
Department of Nutritional Sciences, University of Toronto
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
April 3, 2009
First Posted
April 7, 2009
Study Start
March 1, 2009
Primary Completion
May 1, 2009
Study Completion
May 1, 2009
Last Updated
October 29, 2010
Record last verified: 2010-10