Prevalence of Sleep Apnea in Patients Presenting for Hip or Knee Replacement Surgery

NCT00874822 | Completed Results

• 1 other identifier: 0212-09-EP
• Study Type: observational
• Target: 216
• Locations: 1 country
• Sites: 1

Brief Summary

The study hypothesis is that the prevalence of obstructive sleep apnea in patients presenting for total knee or total hip arthroplasty is higher than generally suspected. The study will include just one arm and results will be compared to a literature control group. Participants referred for preoperative evaluation will be screened using a standard questionnaire. Those at high risk of obstructive sleep apnea will then undergo a formal overnight sleep study (polysomnography).

Conditions

Sleep Apnea, Obstructive

Outcome Measures

Primary Outcomes (1)

• Obstructive Sleep Apnea

  The number patients with obstructive sleep apnea whether newly diagnosed or known at study entry.

  9 Months

Study Arms (1)

Berlin

Patients diagnosed with obstructive sleep apnea by polysomnography after being screened with the Berlin questionnaire.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects are all patients referred to an academic internal medicicine preoperative evaluation clinic prior to hip or knee arthroplasty.

You may qualify if:

• years old and older
• Planned total hip or total knee arthroplasty
• Referral to the internal medicine preoperative evaluation clinic

You may not qualify if:

• None

Sponsors & Collaborators

• University of Nebraska: lead

Study Sites (1)

University of Nebraska Medical Center

Omaha, Nebraska, 68198-3331, United States

Location

Related Publications (5)

• Kaw R, Michota F, Jaffer A, Ghamande S, Auckley D, Golish J. Unrecognized sleep apnea in the surgical patient: implications for the perioperative setting. Chest. 2006 Jan;129(1):198-205. doi: 10.1378/chest.129.1.198.

  PMID: 16424433 BACKGROUND

• Ancoli-Israel S, Kripke DF, Klauber MR, Mason WJ, Fell R, Kaplan O. Sleep-disordered breathing in community-dwelling elderly. Sleep. 1991 Dec;14(6):486-95. doi: 10.1093/sleep/14.6.486.

  PMID: 1798880 BACKGROUND

• Young T, Evans L, Finn L, Palta M. Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women. Sleep. 1997 Sep;20(9):705-6. doi: 10.1093/sleep/20.9.705.

  PMID: 9406321 BACKGROUND

• Gupta RM, Parvizi J, Hanssen AD, Gay PC. Postoperative complications in patients with obstructive sleep apnea syndrome undergoing hip or knee replacement: a case-control study. Mayo Clin Proc. 2001 Sep;76(9):897-905. doi: 10.4065/76.9.897.

  PMID: 11560300 BACKGROUND

• Harrison MM, Childs A, Carson PE. Incidence of undiagnosed sleep apnea in patients scheduled for elective total joint arthroplasty. J Arthroplasty. 2003 Dec;18(8):1044-7. doi: 10.1016/s0883-5403(03)00459-5.

  PMID: 14658110 BACKGROUND

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea Syndromes; Apnea; Respiration Disorders; Respiratory Tract Diseases; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases

Limitations and Caveats

Obstructive sleep apnea was diagnosed in only four patients due to a high rate of failure to undergo PSG by patients for whom it was indicated. A second major weakness is the use of a literature control group.

Results Point of Contact

• Title: Jason Shiffermiller, MD, MPH
• Organization: University of Nebraska Medical Center

jshiffermiller@unmc.edu

402-559-7299

Study Officials

• Jason F Shiffermiller, MD

  University of Nebraska

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 26, 2009
• First Posted: April 3, 2009
• Study Start: May 26, 2009
• Primary Completion: April 11, 2012
• Study Completion: April 11, 2012
• Last Updated: September 18, 2023
• Results First Posted: January 20, 2012

Record last verified: 2023-08

Locations

US (1)