NCT00873210

Brief Summary

Objective of this study is to increase knowledge about safety, tolerability, quality of life and efficacy under conditions of routine use of sunitinib.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
121

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2009

Typical duration for all trials

Geographic Reach
1 country

14 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 30, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 1, 2009

Completed
1 month until next milestone

Study Start

First participant enrolled

May 1, 2009

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2011

Completed
Last Updated

November 9, 2012

Status Verified

November 1, 2012

Enrollment Period

2.5 years

First QC Date

March 30, 2009

Last Update Submit

November 7, 2012

Conditions

Keywords

renal cell carcinomasunitinib malate

Outcome Measures

Primary Outcomes (1)

  • Increased knowledge about safety, tolerability, quality of life and efficacy under conditions of routine use of sunitinib

    36 months

Secondary Outcomes (5)

  • Dose modifications

    36 months

  • Incidence of new diagnosed hypertension

    36 months

  • Incidence of new diagnosed hypothyroidism

    36 months

  • Safety of sunitinib malate in "real-life" setting

    36 months

  • Efficacy of sunitinib malate in "real-life" setting

    36 months

Study Arms (1)

Patients treated with Sutent

125 consecutive patients in outpatient care with advanced or metastatic renal cell carcinoma, that are indicated for 1st or 2nd line anticancer therapy

Drug: Sutent

Interventions

SutentDRUG

50 mg per day for 4 consecutive weeks, followed by 2 weeks treatment pause

Also known as: sunitinib malate
Patients treated with Sutent

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with advanced or metastatic renal cell carcinoma, that are indicated for 1st or 2nd line anticancer therapy.

You may qualify if:

  • Consecutive patients with advanced or metastatic renal cell carcinoma, that are indicated for 1st or 2nd line anticancer therapy

You may not qualify if:

  • Hypersensitivity to sunitinib malate or to any of the excipients
  • Any other contraindication to the use of sunitinib malate (based on decision of the treating physician).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (14)

Pfizer Investigational Site

Banská Bystrica, 975 17, Slovakia

Location

Pfizer Investigational Site

Bojnice, 972 01, Slovakia

Location

Pfizer Investigational Site

Bratislava, 812 50, Slovakia

Location

Pfizer Investigational Site

Bratislava, 833 10, Slovakia

Location

Pfizer Investigational Site

Košice, 043 91, Slovakia

Location

Pfizer Investigational Site

Michalovce, 071 01, Slovakia

Location

Pfizer Investigational Site

Nitra, 949 01, Slovakia

Location

Pfizer Investigational Site

Poprad, 058 01, Slovakia

Location

Pfizer Investigational Site

Prešov, 081 81, Slovakia

Location

Pfizer Investigational Site

Ružomberok, 034 26, Slovakia

Location

Pfizer Investigational Site

Trebišov, 075 01, Slovakia

Location

Pfizer Investigational Site

Trenčín, 911 71, Slovakia

Location

Pfizer Investigational Site

Trnava, 917 75, Slovakia

Location

Pfizer Investigational Site

Žilina, 012 07, Slovakia

Location

Related Links

MeSH Terms

Conditions

Carcinoma, Renal CellKidney Neoplasms

Interventions

Sunitinib

Condition Hierarchy (Ancestors)

AdenocarcinomaCarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsUrologic NeoplasmsUrogenital NeoplasmsNeoplasms by SiteFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesKidney DiseasesUrologic DiseasesMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

PyrrolesAzolesHeterocyclic Compounds, 1-RingHeterocyclic CompoundsIndolesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-Ring

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 30, 2009

First Posted

April 1, 2009

Study Start

May 1, 2009

Primary Completion

November 1, 2011

Study Completion

November 1, 2011

Last Updated

November 9, 2012

Record last verified: 2012-11

Locations