NCT00656955

Brief Summary

Background: In Central Europe, mortality rates for kidney cancers are higher and survival rates are lower than in the United States and Western Europe overall. The Central and Eastern European Renal Cancer Case-Control Study (CEERCC), completed in 2002, offers an opportunity to identify determinants that predict 5-year survival among kidney cancer patients. Objectives: To assess disease recurrence and progression among former participants in the CEERCC. To investigate the effect of genetics, lifestyle factors, medical conditions, occupation and diet on the outcome of kidney cancer patients in Europe. Eligibility: Former participants or next-of-kin of former participants in the CEERCC study. Design: Participants or their next-of-kin are interviewed for 60 minutes and are requested permission to collect relevant information from their or their family member s hospital and cancer registry records.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,002

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2008

Longer than P75 for all trials

Geographic Reach
2 countries

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 11, 2008

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 14, 2008

Completed
3 days until next milestone

Study Start

First participant enrolled

April 17, 2008

Completed
5.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2013

Completed
7.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 17, 2020

Completed
Last Updated

June 18, 2020

Status Verified

June 1, 2020

Enrollment Period

5.1 years

First QC Date

April 11, 2008

Last Update Submit

June 17, 2020

Conditions

Keywords

Kidney CancerMolecular EpidemiologySurvivalOccupational ExposuresRenal Cancer

Outcome Measures

Primary Outcomes (1)

  • Survival

    Cause-specific and overall mortality

    Months of cancer-free survival

Study Arms (1)

Renal cancer patients

Renal cancer patients

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Renal cancer patients

You may qualify if:

  • To be eligible for this study, patients needed to have participated as a histologically confirmed renal cancer case in the previous case-control study entitled Central European Renal Cancer Case-Control (CEERCC) Study which was completed in 2002.

You may not qualify if:

  • Children less than 18 are not eligible to participate in this study because there were no kidney cancer cases observed in the CEERCC Study that were less than 18 years of age.
  • American Indian/Alaskan Native, Asian, Black or African American, Hispanic or Latino, and Native Hawaiian or Pacific Islander.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Dept of Cancer Epidemioology Genetics, Brno, CZ

Brno, Czechia

Location

Olomouc University

Olomouc, Czechia

Location

National Institute of Occupational Medicine, Lodz, Poland

Lodz, Poland

Location

MeSH Terms

Conditions

Kidney Neoplasms

Condition Hierarchy (Ancestors)

Urologic NeoplasmsUrogenital NeoplasmsNeoplasms by SiteNeoplasmsFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesKidney DiseasesUrologic DiseasesMale Urogenital Diseases

Study Officials

  • Mark P Purdue, M.D.

    National Cancer Institute (NCI)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
NIH
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 11, 2008

First Posted

April 14, 2008

Study Start

April 17, 2008

Primary Completion

May 31, 2013

Study Completion

June 17, 2020

Last Updated

June 18, 2020

Record last verified: 2020-06

Locations