NCT00872287

Brief Summary

The attempt to further reduce the operative trauma in laparoscopic cholecystectomy led in new techniques, as Natural Orifice Transluminal Endoscopic Surgery (NOTES) and Single Incision Laparoscopic Surgery (SILS). These new techniques are considered as painless procedures, but there are not any publications to study a possible different pain score in new techniques versus classic laparoscopic cholecystectomy. In this randomized controlled study the researchers have investigated the pain scores, the incidence of nausea and vomiting and analgesics request after the procedure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Sep 2008

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2008

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

March 30, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 31, 2009

Completed
Last Updated

March 31, 2009

Status Verified

March 1, 2009

Enrollment Period

3 months

First QC Date

March 30, 2009

Last Update Submit

March 30, 2009

Conditions

Keywords

minimally invasive surgeryscarless cholecystectomynew techniques in laparoscopyinvisible scarsingle port accessabdominal painshoulder pain

Outcome Measures

Primary Outcomes (1)

  • SILS cholecystectomy, except the invisible scar, has significantly less abdominal and shoulder pain scores

Study Arms (2)

Laparoscopic Cholecystectomy

ACTIVE COMPARATOR

Four ports classic laparoscopic cholecystectomy

Procedure: Laparoscopic Cholecystectomy

SILS

ACTIVE COMPARATOR

Single transumbilical incision laparoscopic cholecystectomy

Procedure: SILS

Interventions

Four ports classic laparoscopic cholecystectomy

Laparoscopic Cholecystectomy
SILSPROCEDURE

Single transumbilical incision laparoscopic cholecystectomy

SILS

Eligibility Criteria

Age28 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body Mass Index less than 30
  • Attacks of cholelithiasis

You may not qualify if:

  • Body Mass Index more than 30
  • Signs of acute cholecystitis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

G. Hatzikosta General Hospital

Ioannina, Epirus, 45001, Greece

Location

Related Publications (1)

  • Tsimoyiannis EC, Tsimogiannis KE, Pappas-Gogos G, Farantos C, Benetatos N, Mavridou P, Manataki A. Different pain scores in single transumbilical incision laparoscopic cholecystectomy versus classic laparoscopic cholecystectomy: a randomized controlled trial. Surg Endosc. 2010 Aug;24(8):1842-8. doi: 10.1007/s00464-010-0887-3. Epub 2010 Feb 20.

MeSH Terms

Conditions

Abdominal PainShoulder Pain

Interventions

Cholecystectomy, Laparoscopic

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsSigns and Symptoms, DigestiveArthralgiaJoint DiseasesMusculoskeletal Diseases

Intervention Hierarchy (Ancestors)

CholecystectomyBiliary Tract Surgical ProceduresDigestive System Surgical ProceduresSurgical Procedures, OperativeLaparoscopyEndoscopyMinimally Invasive Surgical Procedures

Study Officials

  • Evangelos C. Tsimoyiannis, M.D.

    G. Hatzikosta General Hospital, Ioannina, Greece

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 30, 2009

First Posted

March 31, 2009

Study Start

September 1, 2008

Primary Completion

December 1, 2008

Study Completion

December 1, 2008

Last Updated

March 31, 2009

Record last verified: 2009-03

Locations