NCT00842517

Brief Summary

The purpose of this study is to develop a model for long-term maintenance of behavior change by examining the effects of extending the duration of contingency management (CM) for drug abuse on long-term abstinence outcomes. The primary hypothesis is that the Extended (36 week) CM group will have better long-term outcomes as exhibited by greater rates of abstinence at each follow-up assessment as compared to the Standard (12 week) CM group.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
166

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Sep 2004

Longer than P75 for phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2004

Completed
3.1 years until next milestone

First Submitted

Initial submission to the registry

October 24, 2007

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2008

Completed
7 months until next milestone

First Posted

Study publicly available on registry

February 12, 2009

Completed
Last Updated

March 28, 2023

Status Verified

March 1, 2023

Enrollment Period

3.9 years

First QC Date

October 24, 2007

Last Update Submit

March 27, 2023

Conditions

Keywords

Cocaine DependenceCocaine AbuseSubstance AbuseContingency ManagementDrug Treatment

Outcome Measures

Primary Outcomes (1)

  • Duration of cocaine abstinence

    Every 2 weeks for the first year the participant is involved in the study; in addition to 3 month, 6 month, 9 month, 12 month, 15 month, 18 month, 21 month, and 24 month assessment points.

Secondary Outcomes (3)

  • The presence and frequency of non-drug using activities

    3 month, 6 month, 9 month, 12 month, 15 month, 18 month, 21 month, 24 month

  • The presence and frequency of natural contingencies of reinforcement

    3 month, 6 month, 9 month, 12 month, 15 month, 18 month, 21 month, 24 month

  • The presence and frequency of meaningful correlates of long-term behavior change

    Every 2 weeks for the first year the participant is involved in the study; in addition to 3 month, 6 month, 9 month, 12 month, 15 month, 18 month, 21 month, and 24 month assessment points.

Study Arms (2)

Extended

EXPERIMENTAL

36-week duration contingency management program

Behavioral: Contingency Management

Standard

ACTIVE COMPARATOR

12-week duration contingency management program

Behavioral: Contingency Management

Interventions

ExtendedStandard

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Meet DSM-IV criteria for current cocaine dependence or abuse
  • Be willing and able to give valid contact information
  • Be receiving a stable dose of 40 milligrams or more of methadone

You may not qualify if:

  • Are unable to give informed consent (fails simple open-ended consent quiz)
  • Answer yes to the question "Are you in recovery from gambling? That is, have you stopped gambling because of previous problems with gambling?"
  • Report that they have a romantic partner who is already participating in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Parkside Recovery

Philadelphia, Pennsylvania, 19131, United States

Location

MeSH Terms

Conditions

Cocaine-Related DisordersSubstance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental Disorders

Study Officials

  • Kimberly C Kirby, Ph.D.

    Treatment Research Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

October 24, 2007

First Posted

February 12, 2009

Study Start

September 1, 2004

Primary Completion

August 1, 2008

Study Completion

August 1, 2008

Last Updated

March 28, 2023

Record last verified: 2023-03

Locations