NCT00249535

Brief Summary

The purpose of this study is to compare voucher-based contingency management (CM) procedures to a lower-cost CM system that provides opportunities to win prizes. Cocaine-dependent outpatients are randomly assigned to (a) standard treatment, (b) standard treatment plus usual magnitude prize CM, (c) standard treatment plus higher magnitude prize CM, or (d) standard treatment plus voucher CM. Urine and breath samples are collected 2-3x/week for 14 weeks. Follow-up interviews are conducted at 1,3,6 and 9 months following intake during which substance use and psychosocial functioning are assessed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
240

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2005

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2005

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

November 3, 2005

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 7, 2005

Completed
5.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2011

Completed
Last Updated

March 30, 2012

Status Verified

March 1, 2012

Enrollment Period

6.3 years

First QC Date

November 3, 2005

Last Update Submit

March 29, 2012

Conditions

Keywords

Substance AbuseContingency Management

Outcome Measures

Primary Outcomes (1)

  • Cocaine use

    baseline and each follow-up

Study Arms (3)

1

EXPERIMENTAL

standard treatment plus usual magnitude prize CM

Behavioral: Contingency management

2

EXPERIMENTAL

standard treatment plus higher magnitude prize CM

Behavioral: Contingency management

3

EXPERIMENTAL

standard treatment plus voucher CM

Behavioral: Contingency management

Interventions

Rewards (prizes) for abstinence

123

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age \> 18 years
  • current DSM-IV diagnosis of cocaine dependence
  • received methadone treatment at the clinic for at least 3 months
  • on a stable dose of methadone (no changes in dosing) for at least one month and not presently requesting a dose alteration
  • submitted one or more clinic-collected cocaine positive urine samples in the previous 3 months
  • English speaking
  • pass a brief quiz related to understanding of the informed consent form

You may not qualify if:

  • have a serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, bipolar disorder, severe or psychotic major depression, or suicide risk)
  • have dementia (\<23 on the Mini Mental State Exam; Folstein et al. 1975)
  • are in recovery from pathological gambling

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UConn Health Center

Farmington, Connecticut, 06030, United States

Location

MeSH Terms

Conditions

Cocaine-Related DisordersSubstance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental Disorders

Study Officials

  • Nancy Petry, Ph.D.

    UConn Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 3, 2005

First Posted

November 7, 2005

Study Start

March 1, 2005

Primary Completion

July 1, 2011

Study Completion

July 1, 2011

Last Updated

March 30, 2012

Record last verified: 2012-03

Locations