NCT00825461

Brief Summary

The PICOWO research group in corporation with the University of Amsterdam (Artificial Intelligence) has developed a computer simulationmodel of eating disorders (Bosse, Delfos, Jonker \& Treur, 2003). In a running Phd project we want to add ghrelin to the model. The idea for this current research is to collect clinical information about the functioning and (patho)physiology of ghrelin in patients with AN, so we can extend the simulation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2009

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 20, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 21, 2009

Completed
1 month until next milestone

Study Start

First participant enrolled

March 1, 2009

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2012

Completed
Last Updated

January 9, 2018

Status Verified

September 1, 2009

Enrollment Period

2.8 years

First QC Date

January 20, 2009

Last Update Submit

January 5, 2018

Conditions

Keywords

Anorexia Nervosa

Outcome Measures

Primary Outcomes (1)

  • Concentration of ghrelin in blood.

    1 morning

Study Arms (3)

1

Anorexia with tube feeding

2

Anorexia without tube feeding

3

Control

Eligibility Criteria

Age12 Years - 35 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Studypopulation: Patiënts: all female, non -age coupled. Subgroup patients without tube feeding, with tube feeding and a healthy matched control group. Control group: healthy volunteers of the University of Maastricht.

You may qualify if:

  • Studypopulation: Patiënts: all female, non -age coupled.
  • Subgroup patients without tube feeding, with tube feeding and a healthy matched control group.
  • Control group: healty volunteers of the University of Maastricht.

You may not qualify if:

  • Patients with a history of eating disorder different than AN or a psychiatric history.
  • Control group: no history of eating disorders or other psychiatric disabilities. Normal physical examination, ecg, laboratorium (blood cells, liver, kidneys)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Maastricht

Maastricht, Limburg, 6202 AZ, Netherlands

Location

Related Publications (2)

  • Bosse, T.; Delfos., M.F.; Jonker, C.M. & Treur, J. (2003). Reasoning about adaptive Dynamical Systems in the Analysis of eating Regulation Disorders. N.J. Mahwah. Proceedings of the 25th Annual Conference of the Cognitive Science Society. Lawrence Erlbaum Associates Inc.

    BACKGROUND
  • Both, F. & Delfos, M.F. (in preparation). The role of ghrelin in eating disorders, a review.

    BACKGROUND

Biospecimen

Retention: SAMPLES WITH DNA

Whole blood

MeSH Terms

Conditions

Anorexia Nervosa

Condition Hierarchy (Ancestors)

Feeding and Eating DisordersMental Disorders

Study Officials

  • Martine F Delfos, Dr

    PICOWO Utrecht

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 20, 2009

First Posted

January 21, 2009

Study Start

March 1, 2009

Primary Completion

December 1, 2011

Study Completion

December 31, 2012

Last Updated

January 9, 2018

Record last verified: 2009-09

Locations