NCT00813982

Brief Summary

The purpose of this study is to compare an experimental contact lens with a currently marketed contact lens.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2008

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2008

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
21 days until next milestone

First Submitted

Initial submission to the registry

December 22, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 23, 2008

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

October 29, 2010

Completed
Last Updated

May 26, 2023

Status Verified

May 1, 2023

Enrollment Period

1 month

First QC Date

December 22, 2008

Results QC Date

September 3, 2010

Last Update Submit

May 1, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Overall Vision

    Overall vision was interpreted by the subject and recorded on a questionnaire as a single, retrospective evaluation of 1-week wear time. Overall vision was evaluated by eye and rated on a 10-point scale, with 1 being poor and 10 being excellent.

    1 week

Study Arms (2)

Experimental Lotrafilcon A Contact Lens

EXPERIMENTAL

Lotrafilcon A experimental contact lens randomly assigned to one eye

Device: Lotrafilcon A Experimental Contact Lens

Commercial Lotrafilcon A Contact Lens

ACTIVE COMPARATOR

Lotrafilcon A commercial contact lens randomly assigned to one eye

Device: Lotrafilcon A Commercial Contact Lens

Interventions

Experimental spherical, silicone hydrogel soft contact lens

Experimental Lotrafilcon A Contact Lens

Commercially marketed spherical, silicone hydrogel soft contact lens

Commercial Lotrafilcon A Contact Lens

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Able to wear contact lenses for a minimum of 5 days a week, at least 8 hours a day
  • On exam have ocular findings that are considered normal and would not prevent the safe wear of contact lenses

You may not qualify if:

  • Requires concurrent ocular medication
  • Eye injury or surgery within twelve weeks immediately prior to enrollment
  • Evidence of systemic or ocular abnormality, infection, or disease likely to affect successful wear of contact lenses or use of their accessory solutions
  • Any active corneal infection
  • Any use of medications for which contact lens wear would be contraindicated
  • History of corneal refractive surgery
  • Wears toric contact lenses

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Priya Janakiraman, OD, FAAO / Head, Global Clinical Affairs
Organization
CIBA VISION

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 22, 2008

First Posted

December 23, 2008

Study Start

November 1, 2008

Primary Completion

December 1, 2008

Study Completion

December 1, 2008

Last Updated

May 26, 2023

Results First Posted

October 29, 2010

Record last verified: 2023-05