NCT00810511

Brief Summary

The purpose of this trial is to compare two different contact lenses during 4 weeks of wear.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
213

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2008

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2008

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 17, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 18, 2008

Completed
14 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2009

Completed
1.7 years until next milestone

Results Posted

Study results publicly available

October 1, 2010

Completed
Last Updated

December 5, 2023

Status Verified

January 1, 2012

Enrollment Period

2 months

First QC Date

December 17, 2008

Results QC Date

July 23, 2010

Last Update Submit

November 13, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Comfort at End of Day

    Evaluated by the subject as a single, retrospective evaluation of 4-week wear time. Measured on a 10-point scale, with 1 being poor and 10 being excellent.

    After 4 weeks of wear

Study Arms (2)

Lotrafilcon A

EXPERIMENTAL

Investigational, spherical, silicone hydrogel contact lenses

Device: Lotrafilcon A contact lens

Comfilcon A

ACTIVE COMPARATOR

Commercially marketed, spherical, silicone hydrogel contact lenses

Device: Comfilcon A contact lens

Interventions

Silicone hydrogel contact lens

Lotrafilcon A

Silicone hydrogel contact lens

Comfilcon A

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Current soft contact lens wearer who wear their habitual lenses for no less than 10 hours a day, 5 days a week
  • Have a need for correction in both eyes and be correctable to at least 20/40 distance vision in each eye while wearing trial lenses
  • Replace lenses on a weekly or longer schedule

You may not qualify if:

  • Requires concurrent ocular medication
  • Eye injury or surgery within twelve weeks immediately prior to enrollment
  • Evidence of systemic or ocular abnormality, infection, or disease likely to affect successful wear of contact lenses or use of their accessory solutions
  • Current soft toric lens wearers
  • Those who dispose of their soft lenses on a daily basis
  • Current NIGHT \& DAY® or Biofinity® lens wearers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Priya Janakiraman, OD, FAAO / Head, Global Clinical Affairs
Organization
CIBA VISION

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 17, 2008

First Posted

December 18, 2008

Study Start

November 1, 2008

Primary Completion

January 1, 2009

Study Completion

January 1, 2009

Last Updated

December 5, 2023

Results First Posted

October 1, 2010

Record last verified: 2012-01