Effect of β-alanine Supplementation on Muscle Carnosine
LitmusMagnet
Effect of Two 8-week β-alanine Supplementation Protocols on Muscle Carnosine
1 other identifier
interventional
30
1 country
1
Brief Summary
Carnosine is a natural acid buffering substance of muscle. The primary objective of this study is to test whether a nutritional supplement of beta-alanine enhances carnosine content in muscle.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable healthy
Started Dec 2008
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2008
CompletedFirst Submitted
Initial submission to the registry
December 22, 2008
CompletedFirst Posted
Study publicly available on registry
December 23, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2009
CompletedApril 25, 2012
April 1, 2012
10 months
December 22, 2008
April 24, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
muscle carnosine concentration
0 to 8 weeks
Study Arms (3)
beta-alanine 0
PLACEBO COMPARATORbeta-alanine 1
EXPERIMENTALbeta-alanine 2
EXPERIMENTALInterventions
Eligibility Criteria
You may qualify if:
- Stable health as evaluated by medical evaluation
- Body mass index higher than 18 kg/m2
- Body mass index lower than 25 kg/m2, unless body fat is less than 20%
You may not qualify if:
- intolerance to β-alanine,
- allergy to soy, fish and crustacean
- participation in another intervention study
- consumer of dietary supplement susceptible to contain beta-alanine
- determined to have very high baseline muscle carnosine concentration
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Société des Produits Nestlé (SPN)lead
- University of Berncollaborator
- Insel Gruppe AG, University Hospital Berncollaborator
Study Sites (1)
University and Inselspital
Bern, Canton of Bern, 3010, Switzerland
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 22, 2008
First Posted
December 23, 2008
Study Start
December 1, 2008
Primary Completion
October 1, 2009
Study Completion
October 1, 2009
Last Updated
April 25, 2012
Record last verified: 2012-04