Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse

NCT00776685 | Completed Phase 2 DMC

• 1 other identifier: Adventure
• Study Type: interventional
• Target: 3,190
• Locations: 1 country
• Sites: 1

Brief Summary

Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of mental illness. Personality-targeted interventions have been found to have significant preventative effects on onset and growth of drinking, binge-drinking and drinking problems in adolescents attending mainstream schools (Conrod, Castellanos \& Mackie, 2008). The interventions concurrently reduced personality-specific emotional and behavioural problems (Castellanos \& Conrod, 2006), and prevented the onset and escalation of drug-use over a two-year period (Conrod, Castellanos-Ryan \& Strang, 2010). This cluster randomised controlled trial aims to examine whether these results can be replicated when interventions are delivered by trained educational professionals. In addition, the trial will evaluate the broader impact of the programme on cigarette smoking, school attendance, academic achievement and school-wide behaviours.

Conditions

Alcohol Abuse; Drug Abuse; Depression; Panic Disorder; Conduct Disorder

Outcome Measures

Primary Outcomes (5)

• Binge drinking frequency

  Frequency in the past 6 months that subject reported drinking 5 or more alcoholic beverages (4 or more for girls) on one drinking occasion.

  2 years

• Drinking frequency

  Past six months frequency of drinking

  2 years

• drinking quantity

  Average number of alcoholic beverages consumed on a typical drinking occasion in the past six months

  2 years

• Drinking problems

  number of drinking problems reported on an abbreviated version of the Rutger's Alcohol Problem Index.

  2 years

• illicit drug use events

  Time to onset of illicit drug use

  2 years

Secondary Outcomes (1)

• Emotional and behavioural problems, targeted and school-wide effects

  2 years

Study Arms (4)

learning to cope with your impulsivity

EXPERIMENTAL

Cognitive-behavioural intervention targeting impulsive personality

Behavioral: Personality-targeted interventions

learning to cope with your sensation seeking

EXPERIMENTAL

cognitive behavioural intervention designed to help sensation seeking youth manage their need for stimulation and excitement.

Behavioral: Personality-targeted interventions

learning to cope with your anxiety sensitivity

EXPERIMENTAL

cognitive behavioural intervention teaching anxiety sensitive youth to manager their sensitivity to threat and anxiety.

Behavioral: Personality-targeted interventions

learning to manage your negative thinking

EXPERIMENTAL

cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth

Behavioral: Personality-targeted interventions

Interventions

Personality-targeted interventions BEHAVIORAL

Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained teacher and co-facilitator

Also known as: Preventure, but now delivered by teachers

learning to cope with your anxiety sensitivity; learning to cope with your impulsivity; learning to cope with your sensation seeking; learning to manage your negative thinking

Eligibility Criteria

• Age: 13 Years - 16 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Secondary school student

You may not qualify if:

• None

Sponsors & Collaborators

• King's College London: lead
• Action on Addiction: collaborator

Study Sites (1)

Institute of Psychiatry, King's College London

London, United Kingdom

Location

Related Publications (7)

• Conrod PJ, Castellanos-Ryan N, Strang J. Brief, personality-targeted coping skills interventions and survival as a non-drug user over a 2-year period during adolescence. Arch Gen Psychiatry. 2010 Jan;67(1):85-93. doi: 10.1001/archgenpsychiatry.2009.173.

  PMID: 20048226 BACKGROUND

• Conrod PJ, Castellanos N, Mackie C. Personality-targeted interventions delay the growth of adolescent drinking and binge drinking. J Child Psychol Psychiatry. 2008 Feb;49(2):181-90. doi: 10.1111/j.1469-7610.2007.01826.x.

  PMID: 18211277 BACKGROUND

• Conrod PJ, Stewart SH, Comeau N, Maclean AM. Efficacy of cognitive-behavioral interventions targeting personality risk factors for youth alcohol misuse. J Clin Child Adolesc Psychol. 2006 Dec;35(4):550-63. doi: 10.1207/s15374424jccp3504_6.

  PMID: 17007600 BACKGROUND

• O'Leary-Barrett M, Mackie CJ, Castellanos-Ryan N, Al-Khudhairy N, Conrod PJ. Personality-targeted interventions delay uptake of drinking and decrease risk of alcohol-related problems when delivered by teachers. J Am Acad Child Adolesc Psychiatry. 2010 Sep;49(9):954-963.e1. doi: 10.1016/j.jaac.2010.04.011. Epub 2010 Jul 31.

  PMID: 20732631 RESULT

• O'Leary-Barrett M, Castellanos-Ryan N, Pihl RO, Conrod PJ. Mechanisms of personality-targeted intervention effects on adolescent alcohol misuse, internalizing and externalizing symptoms. J Consult Clin Psychol. 2016 May;84(5):438-52. doi: 10.1037/ccp0000082. Epub 2016 Feb 15.

  PMID: 26881449 DERIVED

• Mahu IT, Doucet C, O'Leary-Barrett M, Conrod PJ. Can cannabis use be prevented by targeting personality risk in schools? Twenty-four-month outcome of the adventure trial on cannabis use: a cluster-randomized controlled trial. Addiction. 2015 Oct;110(10):1625-33. doi: 10.1111/add.12991. Epub 2015 Jul 14.

  PMID: 26011508 DERIVED

• Conrod PJ, O'Leary-Barrett M, Newton N, Topper L, Castellanos-Ryan N, Mackie C, Girard A. Effectiveness of a selective, personality-targeted prevention program for adolescent alcohol use and misuse: a cluster randomized controlled trial. JAMA Psychiatry. 2013 Mar;70(3):334-42. doi: 10.1001/jamapsychiatry.2013.651.

  PMID: 23344135 DERIVED

MeSH Terms

Conditions

Alcoholism; Substance-Related Disorders; Depression; Panic Disorder; Conduct Disorder

Condition Hierarchy (Ancestors)

Alcohol-Related Disorders; Chemically-Induced Disorders; Mental Disorders; Behavioral Symptoms; Behavior; Anxiety Disorders; Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders

Study Officials

• Patricia J Conrod, PhD

  King's College London

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: October 17, 2008
• First Posted: October 21, 2008
• Study Start: May 1, 2007
• Primary Completion: March 1, 2010
• Study Completion: May 1, 2010
• Last Updated: June 27, 2011

Record last verified: 2010-12

Locations

GB (1)