NCT00344474

Brief Summary

Personality targeted cognitive behavioural interventions have been shown to be effective in reducing alcohol and drug misuse in adult substance abusers (Conrod et al., 2000) and adolescent drinkers (Conrod et al, in press). As these interventions target personality traits linked to risk for addictive and non-addictive mental disorders, the aim of this study is to examine the extent to which this approach can prevent and/or reduce alcohol and drug misuse as well as have an impact on the onset or severity of emotional and behavioural problems in young people.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
710

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Nov 2003

Longer than P75 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2003

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2006

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

June 22, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 26, 2006

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2008

Completed
Last Updated

June 27, 2011

Status Verified

February 1, 2006

Enrollment Period

2.5 years

First QC Date

June 22, 2006

Last Update Submit

June 24, 2011

Conditions

Alcohol AbuseDrug AbuseDepressionPanic DisorderConduct Disorder

Keywords

PreventionAddictionPersonalityAdolescentsBinge DrinkingAlcohol AbuseComorbidityDepressionAnxietyAntisocial Behaviour

Outcome Measures

Primary Outcomes (3)

  • Time to onset and severity of drug use

    time to illicit drug use events, assessed using the Reckless Behaviour Questionnaire

    2 years

  • Frequency and Quantity of Drinking

    2 years

  • Problem drinking symptoms

    Assessed using an abbreviated version of the Rutger's Alcohol Problem Index

    2 years

Secondary Outcomes (1)

  • Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking

    2 years

Study Arms (4)

learning to cope with your impulsivity

EXPERIMENTAL

cognitive behavioural intervention teaching high impulsive youth how to manage their impulsive thinking and behaviours

Behavioral: PRE-Venture: Personality Risk Education

learning to cope with your sensation seeking

EXPERIMENTAL

cognitive-behavioural intervention teaching high sensation seeking youth how to manage their need for stimulation and excitement

Behavioral: PRE-Venture: Personality Risk Education

learning to cope with your anxiety sensitivity

EXPERIMENTAL

cognitive behavioural intervention targeting catastrophic thinking in high anxiety sensitive youth

Behavioral: PRE-Venture: Personality Risk Education

learning to manage your negative thinking

EXPERIMENTAL

cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth

Behavioral: PRE-Venture: Personality Risk Education

Interventions

PRE-Venture: Personality Risk EducationBEHAVIORAL

Motivational and Cognitive-Behavioural interventions targeting four personality risk factors for substance misuse. Two, 90-minute group sessions conducted at school with personality-matched peers and trained psychologists/councellors and co-facilitators.

learning to cope with your anxiety sensitivitylearning to cope with your impulsivitylearning to cope with your sensation seekinglearning to manage your negative thinking

Eligibility Criteria

Age13 Years - 16 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • secondary school student
  • scoring one standard deviation above the school mean on one of 4 personality dimensions.
  • Able to provide consent from parent/guardian for participation in the study

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute of Psychiatry, King's College London

London, SE5 8AF, United Kingdom

Location

Related Publications (8)

  • Stewart SH, Conrod PJ, Marlatt GA, Comeau MN, Thush C, Krank M. New developments in prevention and early intervention for alcohol abuse in youths. Alcohol Clin Exp Res. 2005 Feb;29(2):278-86. doi: 10.1097/01.alc.0000153547.34399.e8.

    PMID: 15714051BACKGROUND

  • Conrod PJ, Pihl RO, Stewart SH, Dongier M. Validation of a system of classifying female substance abusers on the basis of personality and motivational risk factors for substance abuse. Psychol Addict Behav. 2000 Sep;14(3):243-56. doi: 10.1037//0893-164x.14.3.243.

    PMID: 10998950BACKGROUND

  • Conrod PJ, Stewart SH, Pihl RO, Cote S, Fontaine V, Dongier M. Efficacy of brief coping skills interventions that match different personality profiles of female substance abusers. Psychol Addict Behav. 2000 Sep;14(3):231-42. doi: 10.1037//0893-164x.14.3.231.

    PMID: 10998949BACKGROUND

  • Comeau N, Stewart SH, Loba P. The relations of trait anxiety, anxiety sensitivity, and sensation seeking to adolescents' motivations for alcohol, cigarette, and marijuana use. Addict Behav. 2001 Nov-Dec;26(6):803-25. doi: 10.1016/s0306-4603(01)00238-6.

    PMID: 11768546BACKGROUND

  • Edalati H, Afzali MH, Castellanos-Ryan N, Conrod PJ. The Effect of Contextual Risk Factors on the Effectiveness of Brief Personality-Targeted Interventions for Adolescent Alcohol Use and Misuse: A Cluster-Randomized Trial. Alcohol Clin Exp Res. 2019 May;43(5):997-1006. doi: 10.1111/acer.14016. Epub 2019 Apr 8.

    PMID: 30865304DERIVED

  • Topper LR, Castellanos-Ryan N, Mackie C, Conrod PJ. Adolescent bullying victimisation and alcohol-related problem behaviour mediated by coping drinking motives over a 12 month period. Addict Behav. 2011 Jan-Feb;36(1-2):6-13. doi: 10.1016/j.addbeh.2010.08.016. Epub 2010 Sep 24.

    PMID: 20869813DERIVED

  • O'Leary-Barrett M, Mackie CJ, Castellanos-Ryan N, Al-Khudhairy N, Conrod PJ. Personality-targeted interventions delay uptake of drinking and decrease risk of alcohol-related problems when delivered by teachers. J Am Acad Child Adolesc Psychiatry. 2010 Sep;49(9):954-963.e1. doi: 10.1016/j.jaac.2010.04.011. Epub 2010 Jul 31.

    PMID: 20732631DERIVED

  • Conrod PJ, Castellanos-Ryan N, Strang J. Brief, personality-targeted coping skills interventions and survival as a non-drug user over a 2-year period during adolescence. Arch Gen Psychiatry. 2010 Jan;67(1):85-93. doi: 10.1001/archgenpsychiatry.2009.173.

    PMID: 20048226DERIVED

MeSH Terms

Conditions

AlcoholismSubstance-Related DisordersDepressionPanic DisorderConduct DisorderBehavior, AddictiveBinge DrinkingAnxiety DisordersAntisocial Personality Disorder

Condition Hierarchy (Ancestors)

Alcohol-Related DisordersChemically-Induced DisordersMental DisordersBehavioral SymptomsBehaviorAttention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersCompulsive BehaviorImpulsive BehaviorAlcohol DrinkingDrinking BehaviorPersonality Disorders

Study Officials

  • Patricia J. Conrod, Ph.D.

    Institute of Psychiatry

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
FACTORIAL
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 22, 2006

First Posted

June 26, 2006

Study Start

November 1, 2003

Primary Completion

May 1, 2006

Study Completion

July 1, 2008

Last Updated

June 27, 2011

Record last verified: 2006-02

Locations

GB(1)