NCT00753974

Brief Summary

Use biospecimens procured from patients and organ donors to improve understanding of molecular, cellular, and tissue-level processes produced by cardiovascular disease and therapeutic interventions

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
50mo left

Started Jun 2008

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress82%
Jun 2008Jun 2030

Study Start

First participant enrolled

June 1, 2008

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 16, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 17, 2008

Completed
21.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2030

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2030

Last Updated

August 14, 2025

Status Verified

August 1, 2025

Enrollment Period

22 years

First QC Date

September 16, 2008

Last Update Submit

August 11, 2025

Conditions

Cardiovascular Diseases

Outcome Measures

Primary Outcomes (1)

  • Use biospecimens procured from patients and organ donors to improve understanding of molecular, cellular, and tissue-level processes produced by cardiovascular disease and therapeutic interventions.

    This research aims to advance understanding of cardiovascular disease and to support the development of improved therapies.

    6/26/2008 - 6/9/2030

Study Arms (1)

biological specimen

Biological specimen is taken from cardiovascular procedures that would have been discarded

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

• All patients undergoing cardiovascular surgery/procedure at the University of Kentucky who are at least 18 years of age

You may qualify if:

  • All patients undergoing cardiovascular surgery/procedure at the University of Kentucky who are at least 18 years of age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Kentucky, Department of Internal Medicine, Division of Cardiovascular Medicine

Lexington, Kentucky, 40536, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

Biospecimens procured include myocardium from left and right atria, left and right ventricle, and septum, aortic wall, and venous blood.

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

  • Kenneth S Campbell, PhD

    University of Kentucky

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
PI

Study Record Dates

First Submitted

September 16, 2008

First Posted

September 17, 2008

Study Start

June 1, 2008

Primary Completion (Estimated)

June 1, 2030

Study Completion (Estimated)

June 1, 2030

Last Updated

August 14, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

Locations

US(1)