Emergency Department CT Scanning for Appendicitis
1 other identifier
interventional
244
0 countries
N/A
Brief Summary
The purpose of this study is to compare IV contrast only vs. IV and oral contrast Computed Tomography (CT) for the diagnosis of acute appendicitis in adult patients in our emergency department. A secondary purpose will be to design a specific CT for appendicitis protocol at our institution at the conclusion of this study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Nov 2006
Longer than P75 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2006
CompletedFirst Submitted
Initial submission to the registry
August 12, 2008
CompletedFirst Posted
Study publicly available on registry
August 14, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2010
CompletedJune 28, 2012
June 1, 2012
2 years
August 12, 2008
June 27, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
sensitivity of IV contrast alone for a computed tomography scan for the diagnosis of appendicitis in the adult Emergency Department patient.
immediate reading + blinded reading within 48 hours
Secondary Outcomes (1)
If IV contrast alone for CT scan is sensitive for the diagnosis of appendicitis in the adult Emergency department patient
immediate reading and blinded reading within 48 hours
Study Arms (2)
1
ACTIVE COMPARATORIV contrast
2
ACTIVE COMPARATORIV contrast and oral contrast
Interventions
Eligibility Criteria
You may qualify if:
- years and older who present to the York Hospital Emergency Department with signs and symptoms suggestive of acute appendicitis, but in whom the diagnosis remains unclear as determined by an attending emergency physician or consulting surgeon and in which a CT scan is needed to further assist in the diagnosis
You may not qualify if:
- pregnant patients
- patients with known IV dye or oral contrast allergy
- patients in whom acute appendicitis is not the primary diagnosis
- patients with renal insufficiency that may have significant adverse effect from IV dye
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- WellSpan Healthlead
Related Publications (1)
Kepner AM, Bacasnot JV, Stahlman BA. Intravenous contrast alone vs intravenous and oral contrast computed tomography for the diagnosis of appendicitis in adult ED patients. Am J Emerg Med. 2012 Nov;30(9):1765-73. doi: 10.1016/j.ajem.2012.02.011. Epub 2012 May 23.
PMID: 22633722DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Andrew Kepner, MD
WellSpan Health
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
August 12, 2008
First Posted
August 14, 2008
Study Start
November 1, 2006
Primary Completion
November 1, 2008
Study Completion
September 1, 2010
Last Updated
June 28, 2012
Record last verified: 2012-06