NCT00733941

Brief Summary

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health. The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise. The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2008

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 12, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 13, 2008

Completed
19 days until next milestone

Study Start

First participant enrolled

September 1, 2008

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2009

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
Last Updated

May 27, 2015

Status Verified

May 1, 2015

Enrollment Period

9 months

First QC Date

August 12, 2008

Last Update Submit

May 26, 2015

Conditions

Keywords

Exercise testRunningArterial diameterMonitoring, physiologicOxygen Consumption

Outcome Measures

Primary Outcomes (1)

  • Oxygen uptake

    Before and after the training-, detraining- and retraining-phase

Secondary Outcomes (1)

  • Cardiac function and skeletal muscle enzyme activity

    After training, detraining and retraining

Study Arms (2)

High frequency training

EXPERIMENTAL

24 interval exercises performed 8 times per week

Behavioral: High frequency training

Normal frequency training

EXPERIMENTAL

24 interval exercises performed 3 times per week

Behavioral: normal frequence training

Interventions

24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining

High frequency training

24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Normal frequency training

Eligibility Criteria

Age18 Years - 27 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • BMI\<27, non-smokers, train less that 1-2 times per week, VO2max \<60 for male and \<50 for female.

You may not qualify if:

  • Hypertension, diabetes and cardiovascular disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Norwegian University of Science and Technology

Trondheim, 7020, Norway

Location

NTNU

Trondheim, 7489, Norway

Location

Related Publications (1)

  • Hatle H, Stobakk PK, Molmen HE, Bronstad E, Tjonna AE, Steinshamn S, Skogvoll E, Wisloff U, Ingul CB, Rognmo O. Effect of 24 sessions of high-intensity aerobic interval training carried out at either high or moderate frequency, a randomized trial. PLoS One. 2014 Feb 7;9(2):e88375. doi: 10.1371/journal.pone.0088375. eCollection 2014.

Study Officials

  • Øivind Rognmo, PhD

    Norwegian University of Science and Technology

    PRINCIPAL INVESTIGATOR
  • Ulrik Wisløff, Professor

    National Taiwan Normal University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 12, 2008

First Posted

August 13, 2008

Study Start

September 1, 2008

Primary Completion

June 1, 2009

Study Completion

December 1, 2009

Last Updated

May 27, 2015

Record last verified: 2015-05

Locations