To Explore the Treatment Effect of Various Commercially Available Statins on Patients With Hyperlipidemia
1 other identifier
observational
3,270
1 country
8
Brief Summary
The primary objective is to survey the efficacy of various commercially available statins (a class of lipid-lowering agents, for example, rosuvastatin, atorvastatin, simvastatin, lovastatin, pravastatin and fluvastatin) under local clinical practice in treating patients with hyperlipidemia. Surveillance data (Lipid Profile) will be collected during course of usual clinical practice or captured upon its availability.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2007
8 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2007
CompletedFirst Submitted
Initial submission to the registry
July 29, 2008
CompletedFirst Posted
Study publicly available on registry
July 31, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2009
CompletedDecember 3, 2010
December 1, 2010
1.9 years
July 29, 2008
December 2, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Changes on LDL-C, HDL-C, TG, TC
3~6 months
Secondary Outcomes (3)
ratio for treatment-to-goal
3~6 months
drug compliance
3~6 months
correlation between patient's insight and therapeutic outcome
3~6 months
Study Arms (1)
1
patients with hyperlipidemia newly initiating a statin; or switched from current therapy to a statin, or require dosage adjustment for statin
Eligibility Criteria
based on regular practice and judged by physicians, patients with hyperlipidemia who need to start prescribed with a statin; or to switch from current therapy to a statin, or require dosage adjustment for statin
You may qualify if:
- patients diagnosed with hyperlipidemia
- Patients who are just starting a statin treatment, who need to switch from current therapy to a statin medication, or who are receiving dosage adjustment of statin as judged by the physicians
- Patients who are willing to participate in this study and who sign an informed consent form
You may not qualify if:
- Pregnancy or breast feeding
- Patient are illiterate or unable to fill the questionnaire for any reason
- Patients with contraindications to the use of certain statins as needed prescribed by physicians (as per commercially available statins package insert) including the use of rosuvastatin.
- Any clinical condition which, in the opinion of the attending physician, would not allow safe administration of the study medications
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- AstraZenecalead
Study Sites (8)
Research Site
Changhua, Taiwan
Research Site
Douliu, Taiwan
Research Site
Hualien City, Taiwan
Research Site
Kaohsiung City, Taiwan
Research Site
Pingtung City, Taiwan
Research Site
Taichung, Taiwan
Research Site
Tainan, Taiwan
Research Site
Taipei, Taiwan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Wen-Ter Lai, MD
Kaohsiung Medical University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- INDUSTRY
Study Record Dates
First Submitted
July 29, 2008
First Posted
July 31, 2008
Study Start
December 1, 2007
Primary Completion
November 1, 2009
Study Completion
November 1, 2009
Last Updated
December 3, 2010
Record last verified: 2010-12