Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD
Sequencing
2 other identifiers
interventional
180
1 country
1
Brief Summary
The purpose of this study is to determine whether it is more effective to treat adolescents, with diagnoses of both depression and substance use disorder, with a treatment addressing the substance use first and then treating the depression or to first treat the depression and then treat the substance use or whether treating both disorders simultaneously is most effective. It is expected that treatment of both disorders at the same time will be the most effective.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2008
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2008
CompletedFirst Submitted
Initial submission to the registry
May 16, 2008
CompletedFirst Posted
Study publicly available on registry
May 20, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2013
CompletedMarch 12, 2014
March 1, 2014
4.4 years
May 16, 2008
March 10, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Children's Depression Rating Scale
Intake, Mid-Treatment, Post, 6 months and 12 months follow-up
Secondary Outcomes (1)
Time Life Follow Back
Intake, Mid-Treatment, Post, 6 months and 12 months follow-up
Study Arms (3)
TX1
EXPERIMENTALFunctional Family Therapy (FFT) followed by Adolescent Coping With Depression (ACWD)
TX 2
EXPERIMENTALACWD (Adolescent Coping With Depression) followed by FFT (Functional Family Therapy)
TX 3
EXPERIMENTALCombination of an augmented FFT and ACWD - Integrated treatment
Interventions
ACWD- Cognitive behavioral group therapy for depressed adolescents FFT - Family therapy to address substance use disorders in adolescents
Eligibility Criteria
You may qualify if:
- DSM-IV-TR diagnosis of depression, defined as MDD, dysthymia, or substance-induced mood disorder meeting MDD or dysthymia symptom criteria
- DSM-IV-TR diagnosis of one or more non-nicotine SUD
- Some reported illicit drug use in the last 90 days
- years of age
- parent or guardian willing to participate in study
- basic English competency (ability to converse in English)
You may not qualify if:
- Current and acute suicidal ideation at the level warranting inpatient treatment
- current psychotic symptoms
- the adolescent's sibling is already participating in the study
- if on psychiatric medications, a significant change in dosage levels in the prior 4 weeks -
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Oregon Research Institute
Eugene, Oregon, 97403, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Paul D Rohde, Ph. D.
Oregon Research Institute
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 16, 2008
First Posted
May 20, 2008
Study Start
January 1, 2008
Primary Completion
June 1, 2012
Study Completion
June 1, 2013
Last Updated
March 12, 2014
Record last verified: 2014-03