Effectiveness of Parent-Child Interaction and Emotion Development Therapy in Treating Preschool Children With Depression

NCT00595283 | Completed

• 2 other identifiers: R34MH080163DSIR 84-CTS
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

This study will evaluate the effectiveness of parent-child interaction therapy that includes an emotion development component in treating depression in preschool children.

Conditions

Depression

Keywords

Preschool Onset Major Depressive Disorder; Preschool Depression; Emotion Development; Parent Child Interaction

Outcome Measures

Primary Outcomes (1)

• Depression diagnosis and severity using the Preschool-Age Psychiatric Assessment (PAPA) for major depressive disorder (MDD) module

  Measured at Week 14

Study Arms (2)

1

EXPERIMENTAL

Participants assigned to Parent-Child Interaction Therapy-Emotional Development

Behavioral: Parent Child Interaction Therapy-Emotion Development (PCIT-ED)

2

ACTIVE COMPARATOR

Participants assigned to Developmental Education Parenting Intervention

Behavioral: Developmental Education Parenting Intervention (DEPI)

Interventions

Parent Child Interaction Therapy-Emotion Development (PCIT-ED) BEHAVIORAL

PCIT-ED includes fourteen 1-hour therapy sessions over 14 weeks. Sessions will focus on positive parent-child interactions skills, ways to manage emotions, and relaxation techniques.

Also known as: PCIT-ED

1

Developmental Education Parenting Intervention (DEPI) BEHAVIORAL

DEPI includes 14 weekly, 1-hour education sessions covering a range of child development and parenting topics. Classes are in a small group format and will emphasize emotional and social development.

Also known as: DEPI

2

Eligibility Criteria

• Age: 3 Years - 6 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Meets DSM-IV symptom criteria for MDD based on parent report on PAPA
• Currently resides and has resided with primary caregiver for more than 6 months prior to study entry

You may not qualify if:

• Neurologic disorder (e.g., seizure disorder, closed head injury)
• Autistic spectrum disorder
• Has an IQ of less than 70, based on past testing or clear marked developmental delay
• Currently participating in psychotherapy
• If taking a psychotropic medication, must remain on stable dose of that medication throughout the course of study participation

Sponsors & Collaborators

• Washington University School of Medicine: lead
• National Institute of Mental Health (NIMH): collaborator

Study Sites (1)

Washington University School of Medicine Early Emotional Development Program

St Louis, Missouri, 63108, United States

Location

Related Publications (1)

• Hennefield L, Whalen DJ, Wood G, Chavarria MC, Luby JL. Changing Conceptions of Death as a Function of Depression Status, Suicidal Ideation, and Media Exposure in Early Childhood. J Am Acad Child Adolesc Psychiatry. 2019 Mar;58(3):339-349. doi: 10.1016/j.jaac.2018.07.909. Epub 2019 Jan 8.

  PMID: 30768413 DERIVED

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Study Officials

• Joan L. Luby, MD

  Washington University School of Medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 4, 2008
• First Posted: January 16, 2008
• Study Start: October 1, 2007
• Primary Completion: August 1, 2010
• Study Completion: October 1, 2010
• Last Updated: March 22, 2013

Record last verified: 2013-03

Locations

US (1)