NCT00671177

Brief Summary

Recent studies indicate that infusing 300 milliliters of water (in lieu of air) into the rectum and left colon through the colonoscope as it is being inserted during a colonoscopy examination can allow easier endoscope advancement. This method may prevent stretching of the colon, and ultimately reduce pain induced during colonoscopy. Improvements in patient comfort and cooperation, may increase the efficiency and success rate of complete colonoscopy. The purpose of the study is to test the efficacy of the water immersion technique in patients colonoscopy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
229

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2007

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2007

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

May 1, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 5, 2008

Completed
27 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2008

Completed
8.9 years until next milestone

Results Posted

Study results publicly available

May 1, 2017

Completed
Last Updated

May 1, 2017

Status Verified

March 1, 2017

Enrollment Period

9 months

First QC Date

May 1, 2008

Results QC Date

January 17, 2017

Last Update Submit

March 20, 2017

Conditions

Keywords

colonoscopydiagnostic techniquesdigestive systemendoscopygastrointestinal

Outcome Measures

Primary Outcomes (1)

  • Colonoscopy Success With Minimal Sedation

    At the time of the procedure

Secondary Outcomes (2)

  • Time to Cecum

    At the time of the procedure

  • Patient Satisfaction

    At the time of the procedure

Study Arms (2)

Water Immersion Colonoscopy

EXPERIMENTAL

Water Immersion Colonoscopy

Procedure: water immersion colonoscopy

Standard Air Colonoscopy

ACTIVE COMPARATOR

Standard Air Colonoscopy

Procedure: standard air colonoscopy

Interventions

instillation of 300cc of water in the rectum

Water Immersion Colonoscopy

air instillation in colon for visualization

Standard Air Colonoscopy

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • presentation for colonoscopy
  • male
  • age 18 or older

You may not qualify if:

  • women
  • known inflammatory bowel disease
  • presentation for emergency colonoscopy
  • history of partial colectomy
  • chronic narcotic or benzodiazepine use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Palo Alto Health Care System

Palo Alto, California, 94304, United States

Location

Related Publications (1)

  • Leung CW, Kaltenbach T, Soetikno R, Wu KK, Leung FW, Friedland S. Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation. Endoscopy. 2010 Jul;42(7):557-63. doi: 10.1055/s-0029-1244231. Epub 2010 Jun 30.

MeSH Terms

Conditions

Gastrointestinal Diseases

Condition Hierarchy (Ancestors)

Digestive System Diseases

Results Point of Contact

Title
Dr. Tonya Kaltenbach
Organization
San Francisco VA Medical Center

Study Officials

  • Roy Soetikno, MD, MS

    VA Palo Alto/Stanford University Medical Center

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Professor

Study Record Dates

First Submitted

May 1, 2008

First Posted

May 5, 2008

Study Start

September 1, 2007

Primary Completion

June 1, 2008

Study Completion

June 1, 2008

Last Updated

May 1, 2017

Results First Posted

May 1, 2017

Record last verified: 2017-03

Data Sharing

IPD Sharing
Will not share

Locations