NCT01322724

Brief Summary

The purpose of this study will be to determine if the temperature of water used during insertion of colonoscopy makes a difference in patient discomfort and sedation requirements. The hypothesis of this study is patients receiving screening colonoscopy utilizing the water insertion method with room temperature (cool) water will have similar pain scores and medication requirements compared to water insertion method using body temperature (warm) water.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
175

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2011

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 24, 2011

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 25, 2011

Completed
2 months until next milestone

Study Start

First participant enrolled

June 1, 2011

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2012

Completed
Last Updated

May 25, 2012

Status Verified

May 1, 2012

Enrollment Period

10 months

First QC Date

March 24, 2011

Last Update Submit

May 24, 2012

Conditions

Keywords

colonoscopycolon cancer screeningpatient discomfort scoressedation medication requirementswater insertion method

Outcome Measures

Primary Outcomes (1)

  • Dose of sedation medication used (fentanyl and midazolam)

    Duration of the colonoscopy; Up to 3 hours

Secondary Outcomes (1)

  • Patient pain/discomfort score

    During the day of the procedure; Up to 1 day

Study Arms (2)

Warm water

ACTIVE COMPARATOR

Body temperature (95-100 degrees F) water

Procedure: Warm vs Cool water

Cool water

EXPERIMENTAL

Room temperature (68-73 degrees F) water

Procedure: Warm vs Cool water

Interventions

Body vs Room temperature water used during insertion of colonoscopy

Cool waterWarm water

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults aged 18 to 85 years undergoing elective outpatient screening colonoscopy for colon cancer screening

You may not qualify if:

  • Patients undergoing colonoscopy for any other indication besides colon cancer screening
  • Patients with prior colonic resections
  • Patients with chronic narcotic or benzodiazepine use
  • Poor bowel preparation (i.e. Boston bowel preparation score \< 8)
  • Patients with obstructing colonic lesions detected on colonoscopy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oregon Health & Science University

Portland, Oregon, 97239, United States

Location

Related Publications (1)

  • Lee BY, Katon R, Herzig D, Fennerty MB. Warm water infusion during sedated colonoscopy does not decrease amount of sedation medication used. Gastrointest Endosc. 2012 Dec;76(6):1182-7. doi: 10.1016/j.gie.2012.08.002. Epub 2012 Sep 26.

Study Officials

  • M. Brian Fennerty, MD

    Oregon Health and Science University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 24, 2011

First Posted

March 25, 2011

Study Start

June 1, 2011

Primary Completion

April 1, 2012

Study Completion

April 1, 2012

Last Updated

May 25, 2012

Record last verified: 2012-05

Locations