NCT00643955

Brief Summary

Evaluation of muscle strength and central activation of muscle in individuals with Down Syndrome

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for all trials

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2008

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

March 24, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 26, 2008

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2009

Completed
Last Updated

December 21, 2023

Status Verified

December 1, 2023

Enrollment Period

1 year

First QC Date

March 24, 2008

Last Update Submit

December 15, 2023

Conditions

Down Syndrome

Keywords

Evaluation of muscle strength and central activation

Outcome Measures

Primary Outcomes (1)

  • Muscle strength Central activation ratio

    One time

Study Arms (1)

DS

Individual with Down Syndrome

Other: muscle strength

Interventions

muscle strengthOTHER

muscle strength

DS

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Individuals with Down Snydrome and control subjects without DS

You may qualify if:

  • years old
  • good health with no contraindications to exercise
  • documented DS (not for control subjects)

You may not qualify if:

  • contraindications to exercise,
  • severe or profound MR
  • documented atherosclerotic heart disease
  • documented atlantoaxial instability
  • uncorrected congenital heart disease
  • implanted prosthetic device
  • implanted pacemaker

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IHP

Syracuse, New York, 13210, United States

Location

MeSH Terms

Conditions

Down Syndrome

Interventions

Muscle Strength

Condition Hierarchy (Ancestors)

Intellectual DisabilityNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesAbnormalities, MultipleCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesChromosome DisordersGenetic Diseases, Inborn

Intervention Hierarchy (Ancestors)

Physical ExaminationDiagnostic Techniques and ProceduresDiagnosisMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 24, 2008

First Posted

March 26, 2008

Study Start

March 1, 2008

Primary Completion

March 1, 2009

Last Updated

December 21, 2023

Record last verified: 2023-12

Locations

US(1)