Magnetic Resonance Imaging and Spectroscopy at High Field

NCT00611013 | Withdrawn

• 1 other identifier: UCI-HS-2002-2611
• Study Type: interventional
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Evaluating novel MR imaging techniques on volunteers.

Conditions

Healthy

Keywords

Development of multi-purpose novel imaging protocols

Outcome Measures

Primary Outcomes (1)

• General purpose novel magnetic resonance imaging contrasts, developments for improved magnetic resonance image quality

  10 years

Interventions

Magnetic Resonance Imaging DEVICE

Some participants may receive MRI contrast agent, 0.1 mmol/kg

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy normal volunteers for imaging protocol optimization.

You may not qualify if:

• Patients with implanted surgical clips (hemostatic clips) or other ferromagnetic material,
• Patients engaged in occupations or activities which may cause accidental lodging of ferromagnetic materials, or who may have imbedded metal fragments from military activities,
• Patients with permanent (tattoo) eye-liner or with facial make-up (severe eye irritation has been reported),
• Patients with compromised thermoregulatory systems (e.g. certain cancer patients),
• Patients with metallic implants, because they may cause artifacts in diagnostic images due to magnetic field distortion,
• Patients with implanted prosthetic heart valves,
• Patients with pacemakers, neuro-stimulation devices,
• Pregnant patients (the safety of magnetic resonance examination has not been completely established for embryos and fetuses),
• Subjects who have received orthodontic work involving ferromagnetic materials,
• Subjects who have claustrophobia, and
• The patients unwilling to participate in the study or fail to sign the consent form.
• Subjects who are pregnant or breast-feeding will be excluded from the contrast enhanced MRI studies.
• Subjects who had allergic response to contrast agents previously will be excluded from contrast enhanced MRI studies.
• Subjects with known history of asthma, allergic conditions, severe renal insufficiency, sickle cell anemia, chronic hemolytic anemia, gastrointestinal disorders will also be excluded from contrast enhanced MRI studies.

Sponsors & Collaborators

• University of California, Irvine: lead

Study Sites (1)

Center for Functional Onco-Imaging, University of California

Irvine, California, 92697, United States

Location

MeSH Terms

Interventions

Magnetic Resonance Imaging

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Lutfi T Muftuler, Ph.D.

  University of California, Irvine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: January 12, 2008
• First Posted: February 8, 2008
• Study Start: June 1, 2002
• Primary Completion: July 1, 2012
• Last Updated: June 21, 2013

Record last verified: 2013-06

Locations

US (1)