Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for HCC
HCC
1 other identifier
interventional
84
1 country
1
Brief Summary
Short-term outcomes of laparoscopic liver resection is better than those of open liver resection Laparoscopic liver resection is better than open resection in immunological aspects
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable hepatocellular-carcinoma
Started Dec 2007
Longer than P75 for not_applicable hepatocellular-carcinoma
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2007
CompletedFirst Submitted
Initial submission to the registry
January 21, 2008
CompletedFirst Posted
Study publicly available on registry
February 4, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2017
CompletedOctober 28, 2016
October 1, 2016
9.5 years
January 21, 2008
October 27, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Recurrence rate
2 years after operation
Secondary Outcomes (1)
Survival
2 years after operation
Study Arms (2)
laparoscopic liver resection
EXPERIMENTALPatients who underwent laparoscopic liver resection for HCC
open liver resection
ACTIVE COMPARATORPatients who underwent open liver resection for HCC
Interventions
Laparoscopic or Open hepatectomy
Eligibility Criteria
You may qualify if:
- Radiologically diagnosed hepatocellular carcinoma
- Child classification A or B
- Aged 20 to 80
- Informed consent taken
You may not qualify if:
- Child classification C
- Extrahepatic metastasis
- Tumor located in central area or adjacent to middle hepatic vein
- Recurred hepatocellular carcinoma
- Critically ill patient
- Patient with psychiatric disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 463-707, South Korea
Related Publications (3)
Yoon YS, Han HS, Choi YS, Jang JY, Suh KS, Kim SW, Lee KU, Park YH. Total laparoscopic right posterior sectionectomy for hepatocellular carcinoma. J Laparoendosc Adv Surg Tech A. 2006 Jun;16(3):274-7. doi: 10.1089/lap.2006.16.274.
PMID: 16796440BACKGROUNDMin SK, Han HS, Kim SW, Park YH, Lee HO, Lee JH. Initial experiences with laparoscopy-assisted and total laparoscopy for anatomical liver resection: a preliminary study. J Korean Med Sci. 2006 Feb;21(1):69-74. doi: 10.3346/jkms.2006.21.1.69.
PMID: 16479068BACKGROUNDYoon YS, Han HS, Choi YS, Lee SI, Jang JY, Suh KS, Kim SW, Lee KU, Park YH. Total laparoscopic left lateral sectionectomy performed in a child with benign liver mass. J Pediatr Surg. 2006 Jan;41(1):e25-8. doi: 10.1016/j.jpedsurg.2005.10.068.
PMID: 16410084BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Ho-Seong Han, MD, PhD
Department of Surgery, Seoul National University Bundang Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
January 21, 2008
First Posted
February 4, 2008
Study Start
December 1, 2007
Primary Completion
June 1, 2017
Study Completion
June 1, 2017
Last Updated
October 28, 2016
Record last verified: 2016-10
Data Sharing
- IPD Sharing
- Will not share