NCT00604929

Brief Summary

The present proposal is designed to examine the effect of carbohydrate and protein co-ingestion on muscle protein synthesis during endurance type exercise activities. We hypothesize that muscle protein synthesis is higher when protein is co-ingested during exercise.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable healthy

Timeline
Completed

Started Aug 2008

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 17, 2008

Completed
13 days until next milestone

First Posted

Study publicly available on registry

January 30, 2008

Completed
6 months until next milestone

Study Start

First participant enrolled

August 1, 2008

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2009

Completed
Last Updated

April 14, 2015

Status Verified

April 1, 2015

Enrollment Period

6 months

First QC Date

January 17, 2008

Last Update Submit

April 13, 2015

Conditions

Healthy

Keywords

muscle protein synthesiswhole-body protein breakdownnutrition

Outcome Measures

Primary Outcomes (1)

  • Differences in muscle protein synthesis rates between carbohydrate and carbohydrate + protein.

    1 day

Secondary Outcomes (1)

  • Difference in whole-body protein synthesis and breakdown between carbohydrate and carbohydrate plus protein.

    1 day

Study Arms (1)

1

EXPERIMENTAL
Dietary Supplement: carbohydrate and protein

Interventions

carbohydrate and proteinDIETARY_SUPPLEMENT

The intake of carbohydrate and protein during endurance type exercise

1

Eligibility Criteria

Age18 Years - 28 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • recreationally endurance trained

You may not qualify if:

  • BMI \> 25 kg/m2
  • Not physically active

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

CarbohydratesProteins

Intervention Hierarchy (Ancestors)

Amino Acids, Peptides, and Proteins

Study Officials

  • L van Loon, PhD

    Maastricht University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.

Study Record Dates

First Submitted

January 17, 2008

First Posted

January 30, 2008

Study Start

August 1, 2008

Primary Completion

February 1, 2009

Study Completion

February 1, 2009

Last Updated

April 14, 2015

Record last verified: 2015-04