NCT00588861

Brief Summary

The purpose of this study is to document the clinical outcomes of several devices used in total hip replacement, including the Answer® hip stem, the Ranawat/Burnstein® acetabular shell, and Simplex® or Palacos® bone cement.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2002

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2002

Completed
5.3 years until next milestone

First Submitted

Initial submission to the registry

December 19, 2007

Completed
21 days until next milestone

First Posted

Study publicly available on registry

January 9, 2008

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2010

Completed
1.7 years until next milestone

Results Posted

Study results publicly available

January 26, 2012

Completed
Last Updated

January 27, 2017

Status Verified

January 1, 2012

Enrollment Period

7.7 years

First QC Date

December 19, 2007

Results QC Date

June 14, 2010

Last Update Submit

January 26, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Harris Hip Score

    The Harris Hip Score is detailed below as a range. 100 being the highest score, and 0 being the lowest score. 90-100 is considered "Excellent." 80-89 is considered "Good." 70-79 is considered "Fair." Less than 70 is considered "Poor."

    10 Years Post-Operative

Secondary Outcomes (1)

  • Harris Hip Score Pain

    Pre-Operative, 6 months, 1 year, 2 year, 4 year, 6 year, 8 year, 10 year

Study Arms (2)

Answer® hip stem with Simplex Cement

ACTIVE COMPARATOR

Femoral stem replacement with Answer® hip stem \& Simplex Bone Cement

Device: Answer® hip stem

Answer® hip stem with Palacos Cement

ACTIVE COMPARATOR

Femoral stem replacement with Answer® hip stem \& Palacos Bone Cement

Device: Answer® hip stem

Interventions

Total hip replacement using Palacos® bone cement, the Answer® hip stem and the Ranawat/Burnstein® acetabular shell.

Also known as: Answer Hip Stem, Simplex Bone Cement
Answer® hip stem with Palacos CementAnswer® hip stem with Simplex Cement

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Noninflammatory degenerative joint disease including osteoarthritis and avascular necrosis
  • Rheumatoid arthritis
  • Correction of functional deformity
  • Treatment of non-union, femoral neck fracture, and trochanteric fractures of the proximal femur with head involvement, unmanageable using other techniques

You may not qualify if:

  • Infection, sepsis, and osteomyelitis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Biomet Orthopedics, LLC

Warsaw, Indiana, 46581, United States

Location

MeSH Terms

Conditions

Osteoarthritis, Hip

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Limitations and Caveats

Study was terminated prematurely after sponsor no longer distributed the products involved and follow-up failed to produce sufficient data to be analyzed.

Results Point of Contact

Title
Nick Higdon, Clinical Research Specialist
Organization
Biomet Manufacturing

Study Officials

  • Ken Beres, MD

    Zimmer Biomet

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 19, 2007

First Posted

January 9, 2008

Study Start

September 1, 2002

Primary Completion

May 1, 2010

Study Completion

May 1, 2010

Last Updated

January 27, 2017

Results First Posted

January 26, 2012

Record last verified: 2012-01

Locations