NCT01039337

Brief Summary

The purpose of the study is to evaluate the effect of manual treatment and a patient education programme for patients without indication for hip surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
118

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2008

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2008

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

December 22, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 24, 2009

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2011

Completed
Last Updated

March 30, 2016

Status Verified

March 1, 2016

Enrollment Period

2.7 years

First QC Date

December 22, 2009

Last Update Submit

March 29, 2016

Conditions

Keywords

osteoarthritismanual therapymanipulationhip schoolchiropracticpatient education

Outcome Measures

Primary Outcomes (1)

  • Pain: Numerical pain scale

    Baseline, 6 weeks, 3 months, 1 year

Secondary Outcomes (7)

  • Hip Disability and Osteoarthritis Outcome Score

    Baseline, 6 weeks, 3 months, 1 year

  • General improvement experienced by patient - "Global Assessment"

    Baseline, 6 weeks, 3 months, 1 year

  • Quality of life: EQ-5D

    Baseline, 6 weeks, 3 months, 1 year

  • Passive hip range of motion

    Baseline, 6 weeks, 3 months, 1 year

  • Hip surgery up to one year after baseline

    Baseline, 6 weeks, 3 months, 1 year

  • +2 more secondary outcomes

Study Arms (3)

Hip school

ACTIVE COMPARATOR

This group will receive hip school during the intervention period of 6 weeks.

Other: Hip School

Hip School and Manual Treatment

ACTIVE COMPARATOR

This group receives both hip school and manual treatment during the 6 weeks.

Other: Hip School and Manual Treatment

Minimal control intervention

ACTIVE COMPARATOR

An information leaflet including exercises.

Other: Minimal control intervention

Interventions

The hip school consists of one initial personal interview, three group sessions, and one follow-up personal interview. The hip school is a patient education programme which involves anatomy/physiology, epidemiology, disease progression and pain, advice on self-help and exercises.

Hip school

Hip school as above. Patients receive manual treatment twice a week for 6 weeks. Manual treatment consists of joint manipulation and muscle energy techniques to the articular and soft-tissue structures of the hip.

Hip School and Manual Treatment

As control group, an information leaflet is used with instructions to live as usual during the 6 weeks intervention period. The exercise sheet of the hip school is given to the patients with no further instruction.

Minimal control intervention

Eligibility Criteria

Age40 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients referred from general practitioner, chiropractor or orthopaedic surgeon
  • unilateral hip pain of minimum 3 months' duration
  • radiology criteria for hip OA: joint space width (JSW) \< 2.0 mm or a side difference in JSW of \> 10%
  • adequate mastering of the Danish language to complete instructions and questionnaires

You may not qualify if:

  • inflammatory joint disease
  • previous hip or knee alloplastic
  • secondary arthritis due to hip fracture or infection
  • bilateral hip pain
  • hip dysplasia with a CE angle \> 25 degrees and an AA angle \> 10 degrees
  • low back pain which dominates over the hip pain
  • malignant disease
  • patients with paresis or paralysis after neuromuscular, cerebrovascular or polyneuropathic disease
  • hip pain resulting from labral tear, bursitis and/or snapping hip syndrome
  • polyarthritis
  • received manual treatment for the hip within the last year

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Ortopaedic Surgery and Traumatology, Odense University Hospital

Odense, DK, 5000 C, Denmark

Location

Related Publications (2)

  • Poulsen E, Hartvigsen J, Christensen HW, Roos EM, Vach W, Overgaard S. Patient education with or without manual therapy compared to a control group in patients with osteoarthritis of the hip. A proof-of-principle three-arm parallel group randomized clinical trial. Osteoarthritis Cartilage. 2013 Oct;21(10):1494-503. doi: 10.1016/j.joca.2013.06.009. Epub 2013 Jun 21.

  • Poulsen E, Christensen HW, Roos EM, Vach W, Overgaard S, Hartvigsen J. Non-surgical treatment of hip osteoarthritis. Hip school, with or without the addition of manual therapy, in comparison to a minimal control intervention: protocol for a three-armed randomized clinical trial. BMC Musculoskelet Disord. 2011 May 4;12:88. doi: 10.1186/1471-2474-12-88.

MeSH Terms

Conditions

Osteoarthritis, HipOsteoarthritis

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Officials

  • Erik Poulsen, DC, MSc

    Nordic Institute of Chiropractic and Clinical Biomechanics

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 22, 2009

First Posted

December 24, 2009

Study Start

October 1, 2008

Primary Completion

June 1, 2011

Study Completion

June 1, 2011

Last Updated

March 30, 2016

Record last verified: 2016-03

Locations