Functional, Dynamic, and Anatomic MR Urography

NCT00585767 | Withdrawn

• 1 other identifier: 200311391
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

This is a clinical feasibility study to assess the value of MR imaging for obtaining functional, dynamic and anatomical information in a comprehensive imaging protocol in subjects having obstructive uropathy.

Conditions

Hydronephrosis

Keywords

Hydronephrosis

Study Arms (2)

1

Patients with two kidneys

2

Patients with solitary kidney

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who have been diagnosed with obstructive uropathy

You may qualify if:

• Males or females 18 years of age or older.
• All female patients of childbearing potential must agree to use a medically accepted method of contraception at the time of the study.
• Patients must have the ability to understand the requirements of the study, provide written and informed consent to participate, and agree to abide by the study requirements.
• Patients who have known or suspected hydronephrosis or patients with solitary kidneys.

You may not qualify if:

• Patients with known or suspected hypersensitivity to gadolinium-based agents.
• Patients who are pregnant or lactating.
• Patients with a condition that is a contraindication to MRI (e.g., cardiac pacemaker, epicardial pacemaker leads, cochlear implants, ferromagnetic aneurysm clip, ferromagnetic halo device, or other conditions that would preclude patient proximity to a strong external magnetic field).
• Patients with a recent history of hemolytic anemia, sickle cell anemia or other hemoglobinopathy.
• Patients with a history of significant claustrophobia.
• Patients with impaired renal function based on 24-hr urine collection (creatinine clearance \<10 ml/min or serum creatinine \>1.8 mg/dl)

Sponsors & Collaborators

• University of California, Davis: lead

MeSH Terms

Conditions

Hydronephrosis

Condition Hierarchy (Ancestors)

Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Officials

• Richard Katzburg, MD

  University of California, Davis

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 26, 2007
• First Posted: January 3, 2008
• Study Start: April 1, 2001
• Primary Completion: May 1, 2013
• Study Completion: May 1, 2013
• Last Updated: May 30, 2017

Record last verified: 2017-05