Repeatability of X-Ray, MRI, and Gait Analysis

NCT00581841 | Completed

• 3 other identifiers: R01 AR48768 - substudyR01AR048768NIAMS-081-1
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this preliminary substudy to the parent study "Aerobic Exercise Intervention for Knee Osteoarthritis" is to determine the repeatability and reproducibility of various measurement techniques.

Conditions

Healthy

Keywords

Healthy adult normals

Outcome Measures

Primary Outcomes (1)

• Day-to-day and inter/intra examiner repeatability of the techniques to be used in NIH grant R01 AR48768

  Measured two times, with a 1-week period between evaluations

Study Arms (1)

1

Healthy adult participants with no history of knee injury or osteoarthritis.

Other: Gait analysis, knee x-ray, and knee MRI

Interventions

Gait analysis, knee x-ray, and knee MRI OTHER

Gait analysis, knee x-rays, and knee MRIs will be done twice for each participant, 1 week apart.

1

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Community sample

You may qualify if:

• Healthy adults

You may not qualify if:

• Previous knee injury, knee pain, or knee osteoarthritis

Sponsors & Collaborators

• Mayo Clinic: lead
• National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS): collaborator

Study Sites (1)

Mayo Clinic

Rochester, Minnesota, 55905, United States

Location

Related Publications (4)

• Schmidt JE, Amrami KK, Manduca A, Kaufman KR. Semi-automated digital image analysis of joint space width in knee radiographs. Skeletal Radiol. 2005 Oct;34(10):639-43. doi: 10.1007/s00256-005-0908-9. Epub 2005 May 25.

  PMID: 15915340 BACKGROUND

• Grochowski SJ, Amrami KK, Kaufman K. Semi-automated digital image analysis of patellofemoral joint space width from lateral knee radiographs. Skeletal Radiol. 2005 Oct;34(10):644-8. doi: 10.1007/s00256-005-0944-5. Epub 2005 Jul 15.

  PMID: 16021447 BACKGROUND

• Koff MF, Amrami KK, Kaufman KR. Clinical evaluation of T2 values of patellar cartilage in patients with osteoarthritis. Osteoarthritis Cartilage. 2007 Feb;15(2):198-204. doi: 10.1016/j.joca.2006.07.007. Epub 2006 Sep 1.

  PMID: 16949313 BACKGROUND

• Agnesi F, Amrami KK, Frigo CA, Kaufman KR. Semiautomated digital analysis of knee joint space width using MR images. Skeletal Radiol. 2007 May;36(5):437-44. doi: 10.1007/s00256-006-0245-7. Epub 2007 Jan 23.

  PMID: 17242952 BACKGROUND

MeSH Terms

Interventions

Gait Analysis

Intervention Hierarchy (Ancestors)

Gait; Physical Examination; Diagnostic Techniques and Procedures; Diagnosis; Physical Functional Performance; Physical Fitness; Health; Population Characteristics

Study Officials

• Kenton R. Kaufman, PhD

  Mayo Clinic

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: December 21, 2007
• First Posted: December 28, 2007
• Study Start: November 1, 2002
• Primary Completion: June 1, 2003
• Study Completion: June 1, 2003
• Last Updated: May 17, 2013

Record last verified: 2013-05

Locations

US (1)