Trials Sponsors Conditions Drugs Pricing

Conditions

Cerebrovascular Accident Death, Sudden, Cardiac Myocardial Infarction

Keywords

Cardiovascular EpidemiologyGenomicsGenome-Wide Association Study

Outcome Measures

Primary Outcomes (1)

Genomic regions for each of the four major drug classes that influence drug and gene interaction
Measured at completion of genetic analysis

Secondary Outcomes (1)

Ethnic-specific genetic variations for each of the four major drug classes that influence drug and gene interaction
Measured at completion of genetic analysis

Study Arms (1)

1

Data and specimens from three large population-based studies of heart attack, sudden death, and stroke in people treated for high blood pressure with one of the four major classes of high blood pressure drugs

Eligibility Criteria

Age30 Years - 79 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Data and specimens for this study will be collected from three population-based studies: Group Health population, Cardiovascular Heart Study, and Jackson Heart Study. The Group Health population will provide new DNA samples; the Cardiovascular Heart and Jackson Heart studies will provide existing DNA specimens to replicate the study findings from the Group Health population. The Cardiovascular Heart Study involves Americans over the age of 65. The Jackson Heart Study is a cardiovascular disease study in African Americans.

You may qualify if:

Sponsors & Collaborators

National Heart, Lung, and Blood Institute (NHLBI)
NIHcollaborator
University of Washington
Otherlead

Study Sites (1)

Cardiovascular Health Research Unit

Seattle, Washington, 98101, United States

MeSH Terms

Conditions

Myocardial InfarctionStrokeDeath, Sudden, Cardiac

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosisCerebrovascular DisordersBrain DiseasesCentral Nervous System Diseases

Study Officials

Bruce M. Psaty, MD, PhD
University of Washington
PRINCIPAL INVESTIGATOR

Enrollment

0 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Professor, Medicine & Epidemiology

Study Record Dates

First Submitted

December 12, 2007

First Posted

December 13, 2007

Study Start

September 2007

Date type not reported

This date has not been verified as actual or estimated.

Study Stopped

Analyzing Gene Regions That May Interact With the Effectiveness of High Blood Pressure Drugs

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (1)

1

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (1)

1

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations