Automated Chest Physiotherapy to Improve Outcomes in Neuro

NCT00571623 | Completed

• 1 other identifier: Pro00001842
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 3

Brief Summary

Following current standard-of-care, subjects data (brain pressure) will be recorded for 1 hour and include 10-minutes of data during which the subject recieves chest physiotherapy (CPT). The hypothesis is that CPT is not harmful to brain pressure.

Conditions

Brain Injury; Intracranial Hypertension

Keywords

Brain Injury; Intracranial hypertension; Human subjects; Nursing care

Outcome Measures

Primary Outcomes (1)

• Intracranial pressure

  1 hour

Study Arms (1)

1

All subjects act as their own contral

Other: Chest Physiotherapy

Interventions

Chest Physiotherapy OTHER

10-minutes of chest physiotherapy using programmed parameters that are components of the specialty beds used in ICU

1

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

40 subjects with a neurological diagnosis and current ICP in situ.

You may qualify if:

• documented episode of elevated ICP ICP monitoring in situ neurological/neurosurgical diagnosis currently on a specialy bed

You may not qualify if:

• spinal cord injury such that CPT is not desired

Sponsors & Collaborators

• Duke University: lead
• Neuroscience Nursing Foundation: collaborator

Study Sites (3)

Mission Hospital

Mission Viejo, California, 92691, United States

Location

Duke University

Durham, North Carolina, 27705, United States

Location

WakeMed Hospital

Raleigh, North Carolina, 27610, United States

Location

Related Publications (7)

• Elf K, Nilsson P, Enblad P. Outcome after traumatic brain injury improved by an organized secondary insult program and standardized neurointensive care. Crit Care Med. 2002 Sep;30(9):2129-34. doi: 10.1097/00003246-200209000-00029.

  PMID: 12352052 BACKGROUND

• Grap MJ, Munro CL. Preventing ventilator-associated pneumonia: evidence-based care. Crit Care Nurs Clin North Am. 2004 Sep;16(3):349-58, viii. doi: 10.1016/j.ccell.2004.03.005.

  PMID: 15358383 BACKGROUND

• Olson DM, Thoyre SM, Turner DA, Bennett S, Graffagnino C. Changes in intracranial pressure associated with chest physiotherapy. Neurocrit Care. 2007;6(2):100-3. doi: 10.1007/s12028-007-0015-y.

  PMID: 17522792 BACKGROUND

• Littlejohns L, Bader MK. Prevention of secondary brain injury: targeting technology. AACN Clin Issues. 2005 Oct-Dec;16(4):501-14. doi: 10.1097/00044067-200510000-00007.

  PMID: 16269895 BACKGROUND

• Bader MK, Palmer S. Keeping the brain in the zone. Applying the severe head injury guidelines to practice. Crit Care Nurs Clin North Am. 2000 Dec;12(4):413-27.

  PMID: 11855245 BACKGROUND

• Olson DM, Graffagnino C. Consciousness, coma, and caring for the brain-injured patient. AACN Clin Issues. 2005 Oct-Dec;16(4):441-55. doi: 10.1097/00044067-200510000-00003.

  PMID: 16269891 BACKGROUND

• Arbour R. Aggressive management of intracranial dynamics. Crit Care Nurse. 1998 Jun;18(3):30-40; quiz 41-2. No abstract available.

  PMID: 9677936 BACKGROUND

MeSH Terms

Conditions

Brain Injuries; Intracranial Hypertension

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Wounds and Injuries

Study Officials

• DaiWai M Olson, Phd RN CCRN

  Duke University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 10, 2007
• First Posted: December 12, 2007
• Study Start: September 1, 2007
• Primary Completion: March 1, 2008
• Study Completion: March 1, 2008
• Last Updated: July 9, 2014

Record last verified: 2008-08

Locations

US (3)