NCT00569556

Brief Summary

The purpose of the study is to determine if a nurse managed, protocol driven, disease management process for diabetes results in improved attainment of therapeutic goals for diabetes compared to usual care. It is hypothesized that implementation of the disease management process will improve the percentage of diabetic individuals attaining all three therapeutic targets (HgbA1C\<8.0%, LDL\<100mg/dl, and BP\<130/80mmHG) by 10% compared to usual care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
550

participants targeted

Target at P75+ for not_applicable diabetes-mellitus

Timeline
Completed

Started Sep 2006

Typical duration for not_applicable diabetes-mellitus

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2006

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

December 5, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 7, 2007

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2009

Completed
Last Updated

June 15, 2009

Status Verified

June 1, 2009

Enrollment Period

2.7 years

First QC Date

December 5, 2007

Last Update Submit

June 11, 2009

Conditions

Keywords

Diabetes MellitusChronic Care ModelCase Management

Outcome Measures

Primary Outcomes (1)

  • Combined outcome of BP<130/80 mmHG, HgbA1C<8%, and LDL<100mg/dl at 1 year; the primary analysis will compare the intervention to usual care with respect to the percentage of diabetic individuals achieving all three therapeutic goals

    one year

Secondary Outcomes (1)

  • Safety of the intervention (occurence of adverse events over the course of the trial)

    one year

Study Arms (2)

Usual Care

NO INTERVENTION

Patients receive care through primary care provider

Other: Case Management

Case Management

EXPERIMENTAL

Specially trained nurse case managers contact patients by telephone; monitor blood pressure, LDL, and HgbA1C;, and recommend lifestyle and medication changes as needed

Other: Case Management

Interventions

Phone contact by specially trained nurse case managers; lifestyle recommendations and medication changes as needed

Case ManagementUsual Care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Enrolled at Minneapolis VAMC
  • Type 1 or 2 diabetes
  • Blood pressure at screening visit \> 140mmHg systolic or \> 90mmHg diastolic OR HgbA1C at screening visit \> 9.0% OR LDL at screening visit \> 100mg/dL

You may not qualify if:

  • Primary care provider unwilling to have participant included in study
  • Life expectancy \< 1 year
  • Unable to give consent
  • Severe mental health condition
  • pregnant or planning on becoming pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Minneapolis Veterans Affairs Medical Center

Minneapolis, Minnesota, 55417, United States

Location

Related Publications (1)

  • Ishani A, Greer N, Taylor BC, Kubes L, Cole P, Atwood M, Clothier B, Ercan-Fang N. Effect of nurse case management compared with usual care on controlling cardiovascular risk factors in patients with diabetes: a randomized controlled trial. Diabetes Care. 2011 Aug;34(8):1689-94. doi: 10.2337/dc10-2121. Epub 2011 Jun 2.

MeSH Terms

Conditions

Diabetes Mellitus

Interventions

Case Management

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Patient Care PlanningComprehensive Health CarePatient Care ManagementHealth Services Administration

Study Officials

  • Areef Ishani, MD, MS

    Minneapolis VAMC

    PRINCIPAL INVESTIGATOR
  • Nacide Ercan-Fang, MD

    Minneapolis VAMC

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED

Study Record Dates

First Submitted

December 5, 2007

First Posted

December 7, 2007

Study Start

September 1, 2006

Primary Completion

May 1, 2009

Study Completion

May 1, 2009

Last Updated

June 15, 2009

Record last verified: 2009-06

Locations